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0.5%与0.75%罗哌卡因用于上肢手术锁骨上臂丛神经阻滞的比较研究

A Comparative Study of 0.5% and 0.75% Ropivacaine for Supraclavicular Brachial Plexus Block in Upper Limb Surgery.

作者信息

Ali Nausheen, Dubey Neha, Sahu Shalini, Pandey Anupam, Batra Mahima

机构信息

Department of Anesthesiology, People's College of Medical Sciences and Research Centre, Bhopal, IND.

出版信息

Cureus. 2025 Aug 22;17(8):e90727. doi: 10.7759/cureus.90727. eCollection 2025 Aug.

DOI:10.7759/cureus.90727
PMID:40984941
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12450319/
Abstract

Background For surgery of the upper extremity, one method is the supraclavicular block, as it is a reliable anesthetic, safe, and has a rapid onset. Although for epidural anesthesia, ropivacaine has been studied extensively, few reports exist on its use in supraclavicular brachial plexus block in two different concentrations. The present study was done to evaluate the efficacy of 0.5% ropivacaine for supraclavicular brachial plexus block and to compare it with 0.75% ropivacaine for upper limb surgeries in terms of characteristics of supraclavicular blockade. Methods A prospective, blinded randomized study was conducted, enrolling 60 patients of either sex, American Society of Anesthesiologists (ASA) I and II, who were allocated into two groups in which supraclavicular brachial plexus block was performed using ropivacaine in concentrations of 0.5% and 0.75%, respectively. The onset and duration of sensory and motor blocks were recorded. Results The onset of sensory and motor blockade was faster in patients receiving ropivacaine 0.5% than in those receiving ropivacaine 0.75%. However, the sensory and motor blockade duration was longer in patients who received ropivacaine 0.75%, in comparison to patients who received ropivacaine 0.5%. No statistically significant difference was found in the quality of blocks in both groups. Conclusion Ropivacaine 0.75% provides a longer duration of sensory and motor blockade compared to 0.5% when used for supraclavicular brachial plexus block, making it more suitable for prolonged upper limb surgeries and in cases where prolonged pain relief is prioritized. However, 0.5% may be preferable in cases where early motor recovery is desired. Both concentrations were well-tolerated without any significant complications.

摘要

背景 对于上肢手术,一种方法是锁骨上阻滞,因为它是一种可靠的麻醉方法,安全且起效迅速。虽然对于硬膜外麻醉,罗哌卡因已被广泛研究,但关于其在两种不同浓度下用于锁骨上臂丛神经阻滞的报道很少。本研究旨在评估0.5%罗哌卡因用于锁骨上臂丛神经阻滞的疗效,并就锁骨上阻滞的特点将其与0.75%罗哌卡因用于上肢手术进行比较。方法 进行了一项前瞻性、双盲随机研究,纳入60例美国麻醉医师协会(ASA)分级为I级和II级的男女患者,将其分为两组,分别使用0.5%和0.75%浓度的罗哌卡因进行锁骨上臂丛神经阻滞。记录感觉和运动阻滞的起效时间和持续时间。结果 接受0.5%罗哌卡因的患者感觉和运动阻滞的起效比接受0.75%罗哌卡因的患者更快。然而,与接受0.5%罗哌卡因的患者相比,接受0.75%罗哌卡因的患者感觉和运动阻滞持续时间更长。两组阻滞质量差异无统计学意义。结论 用于锁骨上臂丛神经阻滞时,0.75%罗哌卡因比0.5%罗哌卡因提供更长的感觉和运动阻滞持续时间,使其更适合长时间的上肢手术以及优先考虑长时间缓解疼痛的情况。然而,在期望早期运动恢复的情况下,0.5%可能更可取。两种浓度均耐受性良好,无任何明显并发症。