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结核病和结节病患者的定量免疫电泳分析。

Quantitative immunoelectrophoretic analysis in patients with tuberculosis and sarcoidosis.

作者信息

Clarke H G, Freeman T, Hickman R, Pryse-Phillips W E

出版信息

Thorax. 1970 Jul;25(4):423-6. doi: 10.1136/thx.25.4.423.

DOI:10.1136/thx.25.4.423
PMID:4098613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC514669/
Abstract

A study of 12 immunologically distinct serum proteins has been made in two conditions, tuberculosis and sarcoidosis, which have in common the formation of giant-cell granulomata. Significantly (p<0·001) higher concentrations of five proteins [α group component (GC), caeruloplasmin (caer), haptoglobin (hpt), haemopexin (hpx), and α easily precipitable glycoprotein (α PGp)] were found in tuberculosis. No significant differences from normal were found in patients with sarcoidosis. The results obtained compared to the available figures for conventional electrophoresis and the so-called `acute phase reaction' are discussed.

摘要

对12种免疫性质不同的血清蛋白在两种病症(结核病和结节病)中进行了研究,这两种病症都有巨细胞肉芽肿形成。在结核病患者中发现,五种蛋白质[α组成分(GC)、铜蓝蛋白(caer)、触珠蛋白(hpt)、血红素结合蛋白(hpx)和α易沉淀糖蛋白(αPGp)]的浓度显著升高(p<0·001)。结节病患者与正常情况无显著差异。讨论了所得结果与传统电泳的现有数据以及所谓“急性期反应”的比较情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a561/514669/6ef1340e76f5/thorax00112-0038-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a561/514669/cb7b5bfb103b/thorax00112-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a561/514669/6ef1340e76f5/thorax00112-0038-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a561/514669/cb7b5bfb103b/thorax00112-0038-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a561/514669/6ef1340e76f5/thorax00112-0038-b.jpg

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1
Quantitative immunoelectrophoretic analysis in patients with tuberculosis and sarcoidosis.结核病和结节病患者的定量免疫电泳分析。
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Crossed immunoelectrophoresis: qualitative and quantitative considerations.交叉免疫电泳:定性和定量考量
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2
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Br J Exp Pathol. 1975 Jun;56(3):247-55.
3
[The regulation of acute inflammatory processes by systemic changes of plasma protein profiles].[血浆蛋白谱的系统性变化对急性炎症过程的调节作用]

本文引用的文献

1
STUDIES IN SARCOIDOSIS. II. SERUM PROTEINBOUND CARBOHYDRATES.结节病研究。II. 血清蛋白结合碳水化合物
Acta Med Scand. 1964 Mar;175:373-81.
2
Electrophoretic study of the serum proteins in patients with pulmonary tuberculosis. A series of 122 patients admitted to the Avnstrup Sanatorium.肺结核患者血清蛋白的电泳研究。对阿恩斯特鲁普疗养院收治的122例患者进行了研究。
Acta Tuberc Scand. 1960;39:270-85.
3
[Value of paper electrophoresis in pulmonary tuberculosis; critical and statistical study with reference to 922 examinations in 327 patients].
Naturwissenschaften. 1977 Sep;64(9):471-8. doi: 10.1007/BF00446258.
[纸电泳在肺结核中的价值;对327例患者922次检查的批判性和统计学研究]
Presse Med (1893). 1957 Mar 2;65(18):398-400.
4
[Possibilities and limitations of blood protein electrophoresis in pulmonary tuberculosis].[血液蛋白电泳在肺结核中的可能性与局限性]
Rev Tuberc. 1956 Sep-Oct;20(9-10):938-63.
5
Serum proteins in pulmonary tuberculosis.肺结核中的血清蛋白
Br Med J. 1956 Jun 23;1(4981):1460-4. doi: 10.1136/bmj.1.4981.1460.
6
Electrophoretic studies of the serum proteins in tuberculosis.结核病血清蛋白的电泳研究。
Am Rev Tuberc. 1953 Sep;68(3):372-81. doi: 10.1164/art.1953.68.3.372.
7
Serum proteins and liver function in sarcoidosis.结节病中的血清蛋白与肝功能
Acta Med Scand. 1966 Oct;180(4):449-59. doi: 10.1111/j.0954-6820.1966.tb02857.x.
8
Quantitative immunoelectrophoresis of human serum proteins.人血清蛋白的定量免疫电泳
Clin Sci. 1968 Oct;35(2):403-13.
9
Serum proteins in pulmonary tuberculosis.肺结核中的血清蛋白
Dis Chest. 1967 Dec;52(6):732-45. doi: 10.1378/chest.52.6.732.