Naganawa Hirokazu, Sakamoto Yuichiro, Uemura Yuko, Yamaguchi Ryo, Yoshimoto Daisuke, Recio Maria Kristina, Suzuki Takahiko
Department of Cardiovascular Medicine Toyohashi Heart Center Toyohashi Japan.
J Arrhythm. 2025 Sep 21;41(5):e70196. doi: 10.1002/joa3.70196. eCollection 2025 Oct.
Holter monitoring is widely used to detect atrial tachyarrhythmia (AT) recurrence after catheter ablation (CA) in patients with atrial fibrillation (AF). However, patients experience few subjective symptoms after CA, leading to potential underdiagnosis of recurrence. Two-week Holter monitoring may be more effective compared to 24-h Holter monitoring. This study aimed to evaluate the efficacy of 2-week Holter monitoring for the detection of AT recurrence.
From January 2019 to December 2021, 755 consecutive patients with AF (paroxysmal: 449, persistent: 256, long-standing: 50) who underwent initial CA with wide-area pulmonary vein isolation at our center were enrolled. Two-week Holter monitoring was conducted at 3, 6, 12, 18, and 24 months after CA. Twenty-four-hour Holter monitoring was substituted for the first 24 h of the 2-week Holter monitoring. Freedom from AT recurrence was defined as the absence of AT lasting > 30 s beyond a 3-month blanking period.
Sixty-nine (9.1%) patients dropped out. Among the remaining 686 patients, AT recurrence was detected over the 2-year follow-up period in 173 cases (25.2%) using 2-week Holter monitoring and in 46 cases (6.7%) using 24-h Holter monitoring ( < 0.001). Holter monitoring-based analysis revealed that asymptomatic recurrence was significantly more common in patients with persistent and long-standing AF (85.0%, 96/113 records) compared to those with paroxysmal AF (50.0%, 76/152 records) ( < 0.001).
Two-week Holter monitoring was significantly more effective than conventional 24-h Holter monitoring for detecting AT recurrence after CA, particularly in patients with persistent and long-standing AF.
动态心电图监测广泛用于检测房颤(AF)患者导管消融(CA)术后房性快速性心律失常(AT)的复发情况。然而,患者CA术后主观症状较少,导致复发可能漏诊。与24小时动态心电图监测相比,两周动态心电图监测可能更有效。本研究旨在评估两周动态心电图监测对检测AT复发的有效性。
纳入2019年1月至2021年12月在本中心连续接受初次CA并进行广域肺静脉隔离的755例AF患者(阵发性:449例,持续性:256例,长期持续性:50例)。CA术后3、6、12、18和24个月进行两周动态心电图监测。两周动态心电图监测的前24小时用24小时动态心电图监测替代。无AT复发定义为在3个月空白期后无持续>30秒的AT。
69例(9.1%)患者退出。在其余686例患者中,2年随访期间,使用两周动态心电图监测检测到173例(25.2%)AT复发,使用24小时动态心电图监测检测到46例(6.7%)AT复发(<0.001)。基于动态心电图监测的分析显示,持续性和长期持续性AF患者的无症状复发(85.0%,96/113条记录)明显多于阵发性AF患者(50.0%,76/152条记录)(<0.001)。
对于检测CA术后AT复发,两周动态心电图监测比传统的24小时动态心电图监测显著更有效,尤其是对于持续性和长期持续性AF患者。