Mathew G J, Pace-Floridia A
Can Med Assoc J. 1970 Nov 21;103(11):1143-6.
Cold saline was injected intrathecally for the relief of intractable pain in terminal cancer patients. Worthwhile relief was obtained in five out of seven patients. The procedure should be considered in the management of such cases when neurosurgical procedures have failed or are contraindicated and when patients have become addicted to, or their pain is unrelieved by, narcotics. There is still uncertainty as to whether cold or hypertonicity is the operative factor; we are more in favour of the latter view.
向终末期癌症患者鞘内注射冷盐水以缓解顽固性疼痛。7例患者中有5例获得了显著缓解。当神经外科手术失败或存在禁忌，且患者对麻醉药物成瘾或疼痛未被麻醉药物缓解时，在处理此类病例时应考虑该方法。关于是冷还是高渗性起作用仍存在不确定性；我们更倾向于后一种观点。
