HANBAH评分在评估糖尿病患者死亡率和主要不良心血管事件中的预后意义。
Prognostic significance of HANBAH score in evaluating mortality and major adverse cardiovascular events in patients with diabetes mellitus.
作者信息
Aydemir Selim, Aydın Sidar Şiyar, Altınkaya Onur, Özmen Murat, Çomaklı Nurullah, Aksakal Emrah
机构信息
Department of Cardiology, University of Health Sciences, Erzurum City Hospital, Yakutiye/Erzurum, Erzurum, 25240, Turkey.
Department of Cardiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
出版信息
BMC Cardiovasc Disord. 2025 Sep 24;25(1):659. doi: 10.1186/s12872-025-05132-6.
BACKGROUND
Predicting mortality and major adverse cardiovascular events (MACE) in Type 2 diabetes mellitus (T2DM) is important, but no routinely recommended risk score exists. The HANBAH Score is a recently established risk score for mortality prediction in acute heart failure. This study aimed to investigate the relationship between the HANBAH Score and mortality and MACE in T2DM patients.
METHODS
This study was retrospective, and patients who applied to the outpatient clinic diagnosed with T2DM were included. The patients' HANBAH Score was calculated. The relationship between the HANBAH score and mortality and MACE was examined.
RESULTS
7611 T2DM patients were included in this study. The mean age of the patients was 59.1 ± 12.8 years, and 3187 (41.9%) were male. The mortality rate was 1% (76 patients), and the MACE rate was 5.8% (438 patients). The mean follow-up time was 604 days. HANBAH Score was an independent predictor of mortality (HR: 2.260, 95%CI:1.738-2.939, p < 0.001) and MACE (HR: 1.238, 95%CI:1.094-1.400, p < 0.001). ROC curve analysis showed that HANBAH Score highly predicted mortality (AUC: 0.846, 95%CI: 0.794-0.898, p < 0.001).
CONCLUSIONS
This study showed that the HANBAH Score is a predictor of MACE and mortality in patients with T2DM.
背景
预测2型糖尿病（T2DM）患者的死亡率和主要不良心血管事件（MACE）很重要，但目前尚无常规推荐的风险评分。HANBAH评分是最近建立的用于预测急性心力衰竭死亡率的风险评分。本研究旨在探讨HANBAH评分与T2DM患者死亡率及MACE之间的关系。
方法
本研究为回顾性研究，纳入在门诊诊断为T2DM的患者。计算患者的HANBAH评分。研究HANBAH评分与死亡率及MACE之间的关系。
结果
本研究共纳入7611例T2DM患者。患者的平均年龄为59.1±12.8岁，男性3187例（41.9%）。死亡率为1%（76例患者），MACE发生率为5.8%（438例患者）。平均随访时间为604天。HANBAH评分是死亡率（HR：2.260，95%CI：1.738 - 2.939，p < 0.001）和MACE（HR：1.238，95%CI：1.094 - 1.400，p < 0.001）的独立预测因子。ROC曲线分析显示，HANBAH评分对死亡率具有较高的预测价值（AUC：0.846，95%CI：0.794 - 0.898，p < 0.001）。
结论
本研究表明，HANBAH评分是T2DM患者MACE和死亡率的预测因子。
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