Campo Adriana, Frantz Travis, Borza Monica L, Kirwin David S, Lyford Willis H
Department of Dermatology, Naval Medical Center San Diego, San Diego, USA.
Cureus. 2025 Aug 24;17(8):e90893. doi: 10.7759/cureus.90893. eCollection 2025 Aug.
Eruptive cherry angiomatosis (eCA) is a rare clinical diagnosis. The underlying pathophysiology is unknown, but eCA has been associated with medications, lymphoproliferative disease, graft versus host disease, immunosuppression, and human herpesvirus-8. To our knowledge, there have not been previous reports of eCA in healthy female patients. The goal of this case report is to describe the clinical characteristics and present a novel case series of three otherwise healthy adult women and attempt to characterize common features, comparing patient demographics, any associated comorbidities, clinical presentation, and treatment. Three female patients (aged 52, 42, and 38 years) from Southern California were diagnosed with eCA. All three patients were experiencing hormonal fluctuations at the time of onset, including perimenopause and pregnancy. Despite stabilization of their hormonal conditions, their lesions have persisted. Patient A has had her cherry angiomas treated several times with a 595 nm pulse dye laser; however, her lesions have continued to recur. The other two patients have not sought treatment. All patients are in good health without any significant comorbidities.
爆发性樱桃状血管瘤（eCA）是一种罕见的临床诊断。其潜在的病理生理学尚不清楚，但eCA与药物、淋巴增殖性疾病、移植物抗宿主病、免疫抑制和人类疱疹病毒8有关。据我们所知，此前尚无健康女性患者患eCA的报道。本病例报告的目的是描述临床特征，并呈现一个由三名其他方面健康的成年女性组成的新病例系列，试图通过比较患者人口统计学、任何相关合并症、临床表现和治疗方法来确定共同特征。来自南加州的三名女性患者（年龄分别为52岁、42岁和38岁）被诊断为eCA。所有三名患者在发病时都经历了激素波动，包括围绝经期和妊娠期。尽管她们的激素状况已稳定，但病变仍持续存在。患者A的樱桃状血管瘤已用595纳米脉冲染料激光治疗过几次；然而，她的病变仍不断复发。另外两名患者未寻求治疗。所有患者身体健康，无任何重大合并症。
