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儿童癌症幸存者中与体重指数相关的日常生活活动参与受限情况:一项横断面研究

Body mass index-related participation limitations in daily life activities among survivors of childhood cancer: a cross-sectional study.

作者信息

Tanrıverdi Müberra, Sahin Sedef, Yıldırım Kardelen, Yılmaz Guleser Guney, Davutoglu Ceren, Cakir Fatma Betul, Kaya Kara Özgün

机构信息

Department of Physiotherapy and Rehabilitation, Bezmialem Vakif University, Istanbul, Turkey.

Department of Occupational Therapy, Hacettepe University, Ankara, Turkey.

出版信息

BMJ Paediatr Open. 2025 Sep 25;9(1):e003639. doi: 10.1136/bmjpo-2025-003639.

DOI:10.1136/bmjpo-2025-003639
PMID:40998532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12481326/
Abstract

OBJECTIVES

This study compared participation limitations in daily life activities among childhood cancer survivors across different Body Mass Index (BMI) categories.

DESIGN

Prospective cross-sectional study.

SETTING

The study data were collected from two separate oncology outpatient clinics.

PARTICIPANTS

116 children with cancer aged 10.07±3.83 were included in the study. The mean follow-up time after cancer treatment turnover was 36.28±6.43 months.

PRIMARY OUTCOME MEASURES

Participation levels were assessed using the Pediatric Outcomes Data Collection Instrument (PODCI) as the primary outcome of this study, and they were categorised by BMI.

RESULTS

The mean z score was 0.64 ± 1.12, and the average BMI was 17.76±3.56. The PODCI global functioning score averaged 80.25±15.23. There were no significant associations between the global functioning score and age, chemotherapy, or surgery (p>0.05). However, significant relationships were found between the global functioning score and gender, BMI, and radiotherapy (p<0.05). Significant functional differences were observed in the upper extremity, basic mobility transfer, happiness and overall functioning (p<0.05). No significant differences were noted in sports and physical functioning or pain/comfort across different BMI categories (underweight, normal/healthy, overweight) (p>0.05).

CONCLUSIONS

Survivors experience participation restrictions in daily living activities after completing treatment. Systematic evaluation of feedback received from patients/parents regarding physical function, sports, transfer and participation highlights the importance of BMI in childhood cancer survivors. Addressing these factors is key to achieving better health-related quality of life in functionality and participatory outcomes for survivors.

摘要

目的

本研究比较了不同体重指数(BMI)类别的儿童癌症幸存者在日常生活活动中的参与限制情况。

设计

前瞻性横断面研究。

背景

研究数据收集自两个独立的肿瘤门诊。

参与者

116名年龄为10.07±3.83岁的癌症患儿纳入研究。癌症治疗结束后的平均随访时间为36.28±6.43个月。

主要结局指标

使用儿童结局数据收集工具(PODCI)评估参与水平,将其作为本研究的主要结局指标,并按BMI进行分类。

结果

平均z评分为0.64±1.12,平均BMI为17.76±3.56。PODCI整体功能评分平均为80.25±15.23。整体功能评分与年龄、化疗或手术之间无显著关联(p>0.05)。然而,发现整体功能评分与性别、BMI和放疗之间存在显著关系(p<0.05)。在上肢、基本移动转移、幸福感和整体功能方面观察到显著的功能差异(p<0.05)。在不同BMI类别(体重过轻、正常/健康、超重)的运动和身体功能或疼痛/舒适度方面未发现显著差异(p>0.05)。

结论

幸存者在完成治疗后在日常生活活动中经历参与限制。系统评估从患者/家长那里收到的关于身体功能、运动、转移和参与的反馈,突出了BMI在儿童癌症幸存者中的重要性。解决这些因素是提高幸存者功能和参与结局方面与健康相关生活质量的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/12481326/df6741259e77/bmjpo-9-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/12481326/8eac6f64719f/bmjpo-9-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/12481326/df6741259e77/bmjpo-9-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/12481326/8eac6f64719f/bmjpo-9-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b16/12481326/df6741259e77/bmjpo-9-1-g002.jpg

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本文引用的文献

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Validation and Cultural Adaptation of the Serbian Version of the Pediatric Outcome Data Collection Instrument (PODCI) in Children with Obstetrical Brachial Plexus Lesion.
验证和文化适应在小儿产科臂丛神经损伤的儿科结局数据收集工具(PODCI)的塞尔维亚语版本。
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Influence of Body Mass Index, Cancer Type and Treatment on Long-Term Metabolic and Liver Outcomes in Childhood Cancer Survivors.体重指数、癌症类型及治疗对儿童癌症幸存者长期代谢和肝脏结局的影响
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