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经皮髓内穿刺抽吸、冲洗并注射可吸收骨治疗小儿单纯性骨囊肿的临床疗效

Clinical efficacy of percutaneous intramedullary aspiration, irrigation, and injection of absorbable bone in pediatric simple bone cyst.

作者信息

Xu Gang, Sun Wei, Zhang Shiquan, Li Wei

机构信息

Department of Musculoskeletal Tumor Surgery, First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.

出版信息

Front Pediatr. 2025 Sep 10;13:1672550. doi: 10.3389/fped.2025.1672550. eCollection 2025.

Abstract

BACKGROUND

Simple bone cysts (SBCs) are common benign bone lesions that primarily affect the long bones of children and adolescents. Due to their tendency to recur and their potential to cause pathological fractures, a range of treatment strategies has been investigated. This study evaluates the clinical efficacy of percutaneous intramedullary aspiration, irrigation, and injection of absorbable bone (PAIB) in the treatment of pediatric SBCs.

METHODS

All patients underwent the PAIB procedure. Postoperative evaluation involved radiographic assessment to monitor recurrence and identify potential complications, with magnetic resonance imaging (MRI) performed when clinically indicated.

RESULTS

In this cohort of 36 patients with SBC treated using the PAIB technique, the mean follow-up duration was 33.5 months (range: 12-66 months). Recurrence occurred in 6 patients (16.6%), including one case complicated by a pathological fracture. Five of the recurrent cases underwent repeat PAIB procedures, resulting in complete resolution in two patients. Postoperative imaging revealed small residual cysts in three cases. Bone healing was successfully achieved in 32 patients. Graft bone exudation, identified as a potential risk factor for recurrence, was observed in seven patients. All patients exhibited satisfactory functional outcomes throughout the follow-up period.

CONCLUSION

PAIB appears to be a safe, effective, and minimally invasive treatment option for the management of pediatric simple bone cysts.

摘要

背景

单纯性骨囊肿(SBCs)是常见的良性骨病变,主要影响儿童和青少年的长骨。由于其复发倾向及导致病理性骨折的可能性,人们研究了一系列治疗策略。本研究评估经皮髓内抽吸、冲洗及注入可吸收骨(PAIB)治疗儿童SBCs的临床疗效。

方法

所有患者均接受PAIB手术。术后评估包括影像学评估以监测复发及识别潜在并发症,临床有指征时进行磁共振成像(MRI)检查。

结果

在这组采用PAIB技术治疗的36例SBC患者中,平均随访时间为33.5个月(范围:12 - 66个月)。6例(16.6%)出现复发,其中1例并发病理性骨折。5例复发患者接受了重复PAIB手术,2例患者完全缓解。术后影像学检查发现3例有小的残留囊肿。32例患者成功实现骨愈合。7例患者观察到植骨渗出,这被确定为复发的一个潜在风险因素。所有患者在随访期间功能结局均令人满意。

结论

PAIB似乎是治疗儿童单纯性骨囊肿的一种安全、有效且微创的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce38/12457316/3df89482f8c3/fped-13-1672550-g001.jpg

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