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上消化道内镜检查中的支架及新兴替代方案:全面综述

Stents and Emerging Alternatives in Upper Gastrointestinal Endoscopy: A Comprehensive Review.

作者信息

Bernardi Francesca, Dell'Anna Giuseppe, Biamonte Paolo, Barchi Alberto, Fanti Lorella, Malesci Alberto, Fuccio Lorenzo, Sinagra Emanuele, Calabrese Giulio, Facciorusso Antonio, Bruni Angelo, Donatelli Gianfranco, Danese Silvio, Mandarino Francesco Vito

机构信息

Gastroenterology and Gastrointestinal Endoscopy Division, IRCCS San Raffaele Hospital, Via Olgettina 60, 20132 Milan, Italy.

Faculty of Medicine and Surgery, Vita-Salute San Raffaele University, Via Olgettina 56, 20132 Milan, Italy.

出版信息

Diagnostics (Basel). 2025 Sep 16;15(18):2344. doi: 10.3390/diagnostics15182344.

DOI:10.3390/diagnostics15182344
PMID:41008715
Abstract

Endoscopy has revolutionized the management of gastrointestinal (GI) conditions, enabling less invasive treatments for cases that once required surgery. Among these innovations, endoscopically placed stents have played a crucial role in the treatment of upper GI tract diseases for many years. Today, stents remain a valid first-line treatment for specific indications; however, advancements in endoscopic technologies have led to a reassessment of their role in some conditions. While stents are still the primary choice for palliation of malignant esophageal strictures, endoscopic vacuum therapy (EVT) has demonstrated superior outcomes for esophageal leaks, and Endoscopic UltraSonography-guided placement of lumen-apposing metal stents (LAMS) has outperformed traditional stents in gastric obstructions. This review evaluates current stent indications, highlighting upper GI conditions where they remain the best option, while also exploring emerging technologies and updated clinical guidelines to optimize patient care.

摘要

内镜检查彻底改变了胃肠道疾病的治疗方式,使曾经需要手术治疗的病例能够采用侵入性较小的治疗方法。在这些创新技术中,内镜下放置支架多年来在上消化道疾病的治疗中发挥了关键作用。如今,对于特定适应症,支架仍然是一种有效的一线治疗方法;然而,内镜技术的进步导致人们重新评估了它们在某些情况下的作用。虽然支架仍然是恶性食管狭窄姑息治疗的主要选择,但内镜真空治疗(EVT)在食管漏的治疗中已显示出更好的效果,并且内镜超声引导下放置管腔贴附金属支架(LAMS)在胃梗阻的治疗中比传统支架表现更优。本综述评估了当前支架的适应症,突出了它们仍然是最佳选择的上消化道疾病情况,同时也探讨了新兴技术和更新的临床指南,以优化患者护理。

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本文引用的文献

1
Endoscopic ultrasonography-guided gastroenterostomy versus uncovered duodenal metal stenting for unresectable malignant gastric outlet obstruction (DRA-GOO): a multicentre randomised controlled trial.内镜超声引导下胃造口术与裸金属十二指肠支架置入术治疗不可切除的恶性胃出口梗阻(DRA-GOO):一项多中心随机对照试验
Lancet Gastroenterol Hepatol. 2025 Jun;10(6):e8-e16. doi: 10.1016/S2468-1253(25)00136-0.
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Endoscopic ultrasound gastroenterostomy vs duodenal stenting for malignant gastric outlet obstruction: Cost-effectiveness study.内镜超声引导下胃造口术与十二指肠支架置入术治疗恶性胃出口梗阻的成本效益研究
Endosc Int Open. 2025 Mar 12;13:a25097671. doi: 10.1055/a-2509-7671. eCollection 2025.
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EUS-Guided Gastroenterostomy for Benign Gastric Outlet Obstruction: A Systematic Review and Meta-analysis.
超声内镜引导下胃造瘘术治疗良性胃出口梗阻:一项系统评价和荟萃分析
J Clin Gastroenterol. 2025 Jan 3. doi: 10.1097/MCG.0000000000002130.
4
Long-Term Outcomes of EUS-Guided Gastroenterostomy: A Large, Single-Center Experience.超声内镜引导下胃肠造口术的长期疗效:一项大型单中心经验
Clin Transl Gastroenterol. 2025 Jan 1;16(1):e00648. doi: 10.14309/ctg.0000000000000648.
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Endoscopic ultrasound-guided gastrojejunostomy with wire endoscopic simplified technique: Move towards benign indications (with video).内镜超声引导下带导丝内镜简化技术胃空肠吻合术:迈向良性适应证(附视频)
Dig Endosc. 2025 Feb;37(2):167-175. doi: 10.1111/den.14895. Epub 2024 Sep 10.
6
Risk factors of stent migration in esophageal cancer patients who underwent fully-covered self-expanding metal stents for malignant dysphagia or tracheoesophageal fistula.接受全覆膜自膨式金属支架治疗恶性吞咽困难或气管食管瘘的食管癌患者支架移位的危险因素。
J Formos Med Assoc. 2025 May;124(5):432-438. doi: 10.1016/j.jfma.2024.05.014. Epub 2024 May 31.
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Adverse events with endoscopic ultrasound-guided gastroenterostomy for gastric outlet obstruction-A systematic review and meta-analysis.内镜超声引导下胃造口术治疗胃出口梗阻的不良事件:系统评价和荟萃分析。
United European Gastroenterol J. 2024 Sep;12(7):879-890. doi: 10.1002/ueg2.12576. Epub 2024 May 15.
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Surg Endosc. 2024 Jun;38(6):2995-3003. doi: 10.1007/s00464-024-10817-8. Epub 2024 Apr 22.
9
Palliative procedures for malignant gastric outlet obstruction: a network meta-analysis.恶性胃出口梗阻的姑息治疗:一项网状荟萃分析。
Endoscopy. 2024 Oct;56(10):780-789. doi: 10.1055/a-2309-7683. Epub 2024 Apr 19.
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J Clin Med. 2024 Jan 9;13(2):357. doi: 10.3390/jcm13020357.