Beversdorf David Q
Department of Neurology, Radiology, and Psychological Science, William and Nancy Thompson Endowed Chair in Radiology, University of Missouri, Columbia, MO 65211, USA.
Behav Sci (Basel). 2025 Aug 30;15(9):1185. doi: 10.3390/bs15091185.
A range of factors affect performance on tasks associated with creativity, including stress, pharmacology, behavioral interventions, and neural stimulation strategies. Most of the pharmacological impacts have focused on the dopaminergic and noradrenergic systems. However, some evidence suggests that these systems may differ in their impact on performance on divergent and convergent tasks. We performed a systematic PubMed review examining the results for 'creativity and (dopamine or dopaminergic)' and 'creativity and (norepinephrine or noradrenergic or adrenergic)'. The dopaminergic search yielded 238 articles. The noradrenergic search yielded 102 articles. The articles were screened for actually targeting these systems (for example, by pharmacological intervention or by examining genetics relevant to these systems) and examining performance on divergent or convergent tasks. Results of the review of the qualifying articles lent some support to an impact of the dopaminergic system on divergent task performance, and suggested an impact of the noradrenergic system on convergent task performance, but often required additional factors such as stress to reveal robust effects. This review suggests a differential impact of the dopaminergic system and noradrenergic system on divergent and convergent task performance, but studies to systematically address this question across conditions are lacking, and would be needed going forward.
一系列因素会影响与创造力相关任务的表现，包括压力、药理学、行为干预和神经刺激策略。大多数药理学影响都集中在多巴胺能和去甲肾上腺素能系统上。然而，一些证据表明，这些系统对发散性任务和聚合性任务表现的影响可能有所不同。我们对PubMed进行了系统综述，研究“创造力与（多巴胺或多巴胺能）”以及“创造力与（去甲肾上腺素或去甲肾上腺素能或肾上腺素能）”的结果。多巴胺能检索产生了238篇文章。去甲肾上腺素能检索产生了102篇文章。对这些文章进行筛选，以确定其是否实际针对这些系统（例如，通过药理学干预或通过研究与这些系统相关的遗传学）以及是否研究了发散性或聚合性任务的表现。对符合条件的文章的综述结果为多巴胺能系统对发散性任务表现的影响提供了一些支持，并表明去甲肾上腺素能系统对聚合性任务表现有影响，但通常需要压力等额外因素才能揭示出显著效果。本综述表明多巴胺能系统和去甲肾上腺素能系统对发散性和聚合性任务表现有不同影响，但缺乏跨条件系统解决这一问题的研究，未来仍需要此类研究。
