Alausa K O, Montefiore D, Sogbetun A O, Ashiru J O, Onile B A, Sobayo E
Scand J Infect Dis. 1977;9(3):181-5. doi: 10.3109/inf.1977.9.issue-3.05.
A prospective study showed that during the first 6 months of 1976, 146 patients out of a total of 3938 admitted to a hospital in Nigeria were suffering from septicaemia, or developed the condition while in hospital. Findings differed from those reported from developed countries in that the majority of infections were community acquired, those most frequently and severely affected were the very young, and salmonella spp. and Staphylococcus aureus were the most important pathogens. However, other gram-negative organisms, particularly klebsiella spp. and Pseudomonas aeruginosa also occurred frequently among the very young, in whom they produced a high mortality. The type of epidemiological pattern, and the bacteria responsible for the bloodstream infections reflect a differing age structure of the population in tropical countries from that in temperature developed countries, as well as the fact that bacterial infections are still one of the most important causes of illness and hospital admission among tropical communities.
一项前瞻性研究表明，在1976年的前6个月里，尼日利亚一家医院收治的3938名患者中，有146人患有败血症，或在住院期间患上此病。研究结果与发达国家报告的结果不同，在于大多数感染是社区获得性的，受影响最频繁且最严重的是幼儿，沙门氏菌属和金黄色葡萄球菌是最重要的病原体。然而，其他革兰氏阴性菌，特别是克雷伯菌属和铜绿假单胞菌在幼儿中也很常见，它们在幼儿中导致了很高的死亡率。这种流行病学模式的类型以及导致血流感染的细菌，反映出热带国家的人口年龄结构与温带发达国家不同，也反映出细菌感染仍是热带社区疾病和住院的最重要原因之一。
