Percy-Robb I W, Cruikshank D, Lamont L, Whitby L G
Br Med J. 1971 Mar 13;1(5749):596-9. doi: 10.1136/bmj.1.5749.596.
Follow-up studies of findings obtained during a short programme of biochemical screening conducted on 1,041 patients attending their general practitioners in January 1967 showed that this yielded 64 results that led to a change in diagnosis or method of treatment. These results were obtained in 57 patients (5.5% of patients screened), whereas only 15 abnormal results would have been revealed on 14 of the 1,041 patients if the tests performed had been restricted to those requested on the basis of clinical features. Hence a screening programme can make an important contribution to the recognition of otherwise unsuspected disease.
对1967年1月在全科医生处就诊的1041名患者进行的短期生化筛查结果的后续研究表明，该筛查产生了64项导致诊断或治疗方法改变的结果。这些结果出现在57名患者中（占筛查患者的5.5%），而如果仅进行基于临床特征要求的检测，在1041名患者中的14名患者身上只会发现15项异常结果。因此，筛查计划可为识别其他未被怀疑的疾病做出重要贡献。
