Suppr超能文献

少即是多吗?有限手术治疗脊柱包虫囊肿并不充分。

Is Less More? Limited Surgery Is Insufficient in the Treatment of Spinal Hydatid Cysts.

作者信息

Sarac Mustafa Emre, Boga Zeki, Olguner Semih Kivanc, Arslan Ali, Çınkı Ahmet Hamit, Ozer Mehmet, Gezercan Yurdal

机构信息

Department of Neurosurgery, Adana City Traininig and Research Hospital, Adana 01230, Turkey.

出版信息

J Clin Med. 2025 Sep 17;14(18):6540. doi: 10.3390/jcm14186540.

Abstract

: Spinal hydatid disease frequently poses significant surgical challenges and leads to severe neurological complications. Despite the development of various surgical techniques, recurrence remains a common issue. The aim of this study was to evaluate the impacts of radical vertebrectomy on recurrence and long-term follow-up outcomes by comparing total en-bloc spondylectomy with conventional laminectomy, decompression, and posterior stabilisation in patients treated at our centre. : This study included 21 patients who underwent surgery for spinal hydatid cysts at our centre between 2001 and 2021. Twelve patients had cystectomy, laminectomy, decompression, and stabilisation, and nine patients had total en-bloc spondylectomy. A single senior surgeon carried out each procedure, selecting the surgical approach based on the presence of vertebral body involvement. All patients received albendazole treatment for six months following surgery. The surgeon who performed the operations followed up all patients clinically and radiologically for at least three years. Seven out of twelve patients (58.3%) who had conventional surgery experienced recurrences, while total en-bloc spondylectomy produced no recurrences ( = 0.004). The recurrent cases had a mean of 2.8 surgical procedures and manifested within 14 months. Although total en-bloc spondylectomy was associated with a longer operative time and greater blood loss, neurological recovery and overall clinical outcomes were comparable between the two groups. The difference in the recurrence rate was statistically significant. : Although technically demanding, radical vertebrectomy is shown to provide complete protection against recurrence in appropriately selected patients with spinal hydatid disease in this study. Furthermore, as conservative approaches often require multiple procedures, total en-bloc spondylectomy can be considered an effective treatment for patients with vertebral body involvement.

摘要

脊柱包虫病常常带来重大的手术挑战,并导致严重的神经并发症。尽管各种手术技术不断发展,但复发仍是一个常见问题。本研究的目的是通过比较全椎体整块切除术与传统椎板切除术、减压术和后路稳定术,评估根治性椎体切除术对复发率和长期随访结果的影响,研究对象为在本中心接受治疗的患者。

本研究纳入了2001年至2021年间在本中心接受脊柱包虫囊肿手术的21例患者。12例患者接受了囊肿切除术、椎板切除术、减压术和稳定术,9例患者接受了全椎体整块切除术。每例手术均由一位资深外科医生进行,根据椎体受累情况选择手术方式。所有患者术后均接受了6个月的阿苯达唑治疗。实施手术的外科医生对所有患者进行了至少三年的临床和影像学随访。接受传统手术的12例患者中有7例(58.3%)复发,而全椎体整块切除术无一例复发(P = 0.004)。复发病例平均接受了2.8次手术,且在14个月内出现复发。尽管全椎体整块切除术的手术时间更长、失血量更大,但两组患者神经功能恢复情况和总体临床结果相当。复发率的差异具有统计学意义。

尽管技术要求较高,但本研究表明,根治性椎体切除术在适当选择的脊柱包虫病患者中可提供完全预防复发的保护。此外,由于保守治疗方法通常需要多次手术,全椎体整块切除术可被视为椎体受累患者的一种有效治疗方法。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验