Guarnieri Renzo, Reda Rodolfo, Di Nardo Dario, Miccoli Gabriele, Zanza Alessio, Testarelli Luca
Private Periodontal Implant Practice, 31100 Treviso, Italy.
Dentistry Departement, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128 Rome, Italy.
J Clin Med. 2025 Sep 17;14(18):6546. doi: 10.3390/jcm14186546.
The aim of the study was to investigate the risk factors related to early implant failures in patients treated in a private implant clinic. The study was retrospectively conducted on 392 patients (mean age = 51.2 ± 15.4 years, 48.9% female and 51.1% male) who received 930 dental implants within the period from 2000 to 2020. Included patients had received at least one implant. Patients were excluded in case of incomplete dental records that did not contain the necessary information, including personal information (patient's name, age, gender, history and current condition of systemic diseases) and treatment protocol record. No patients were excluded on the basis of systemic disease if it did not contraindicate dental implant surgery. Patient-related variables (age, gender, smoking, history of periodontitis, accompanying disease), surgical-related variables (surgical technique, bone augmentation, lateral sinus lift, internal sinus lift, immediate implant placement after tooth extraction, immediate mucosal grafting, insertion torque,) and implant-related variables (implant design, implant level, implant surface, site of implant placement, implants diameter, length and implants brand name) were recorded. GEE analysis results showed that the implant-based failure rate before or at the abutment connection stage was 5.8%. Seven factors were identified associated with early implant failures: male gender, smoking, history of radiotherapy and chemotherapy, maxilla implant placement, non-submerged healing method, implant design and implant brand. In light of the results obtained, both patient-related variables (gender, smoking, history of radiotherapy and chemotherapy) and variables related to the type of implant, its position and the surgical technique used (maxilla implant placement, non-submerged healing method, implant design and implant brands) were found to be statistically correlated with early failures in this study.
本研究的目的是调查在一家私立种植牙诊所接受治疗的患者早期种植失败的相关危险因素。该研究对2000年至2020年期间接受930颗牙种植体的392例患者（平均年龄 = 51.2 ± 15.4岁，女性占48.9%，男性占51.1%）进行了回顾性分析。纳入的患者至少接受了一颗种植体。如果牙科记录不完整，未包含必要信息，包括个人信息（患者姓名、年龄、性别、全身疾病史和当前状况）以及治疗方案记录，则将患者排除。如果全身疾病不 contraindicate 牙种植手术，则不会基于该疾病排除患者。记录了与患者相关的变量（年龄、性别、吸烟、牙周炎病史、伴随疾病）、与手术相关的变量（手术技术、骨增量、外侧窦提升、内侧窦提升、拔牙后即刻种植、即刻黏膜移植、植入扭矩）以及与种植体相关的变量（种植体设计、种植体水平、种植体表面、种植体植入部位、种植体直径、长度和种植体品牌名称）。广义估计方程（GEE）分析结果显示，基台连接阶段之前或之时基于种植体的失败率为5.8%。确定了七个与早期种植失败相关的因素：男性、吸烟、放疗和化疗史、上颌种植体植入、非潜入式愈合方法、种植体设计和种植体品牌。根据获得的结果，在本研究中发现与患者相关的变量（性别、吸烟、放疗和化疗史）以及与种植体类型、其位置和所使用的手术技术相关的变量（上颌种植体植入、非潜入式愈合方法、种植体设计和种植体品牌）与早期失败在统计学上相关。
