癫痫的外科治疗

Rapport R L, Ojemann G A, Wyler A R, Ward A A

West J Med. 1977 Sep;127(3):185-9.

Therapy with anticonvulsant drugs reduces the frequency and severity of seizures in many but not all epileptic patients. Unfortunately, in a significant number control remains poor even when maximal doses of multiple anticonvulsant drugs are given. Some of these patients are candidates for surgical treatment of epilepsy. The operative management of convulsive disorders is a well-established technique and is available in some centers. In selected cases, such operations are both safe and effective, with good longterm improvement or complete control in 76 percent of patients. We have summarized the 24-year experience with surgical operation for epilepsy at the University of Washington Medical Center.

抗惊厥药物治疗可降低许多（但并非所有）癫痫患者癫痫发作的频率和严重程度。不幸的是，即使给予多种抗惊厥药物的最大剂量，仍有相当数量的患者病情控制不佳。其中一些患者适合接受癫痫手术治疗。惊厥性疾病的手术治疗是一项成熟的技术，在一些中心可以开展。在特定病例中，此类手术既安全又有效，76%的患者能获得良好的长期改善或完全控制。我们总结了华盛顿大学医学中心24年的癫痫手术经验。