Bhatia R, Kollevold T
Epilepsia. 1976 Mar;17(1):61-6. doi: 10.1111/j.1528-1157.1976.tb03383.x.
Ninety-one patients operated on for focal epilepsy between 1952 and 1973 have been followed regularly. Nontumoral lesions were found in 68 patients, and tumors in 23. Of the 50 patients without tumor who have been followed for more than 2 years, 30% were seizure-free, 50% improved, while only 20% did not benefit from the operation. There was no operative mortality. Ventricular asymmetry in the pneumoencephalogram was associated with a better prognosis than when there was no or symmetrical enlargement. The time between the onset of seizures and the operation did not affect the prognosis, but early operation is important to achieve better and quicker rehabilitation. There was a positive correlation between the postoperative ECoG and EEG and the clinical results.
1952年至1973年间接受局灶性癫痫手术的91例患者得到了定期随访。68例患者发现有非肿瘤性病变,23例发现有肿瘤。在50例无肿瘤且随访超过2年的患者中,30%无癫痫发作,50%病情改善,而只有20%未从手术中获益。无手术死亡病例。气脑造影显示的脑室不对称与较好的预后相关,相比无扩大或对称扩大时预后更佳。癫痫发作开始至手术的时间并不影响预后,但早期手术对于实现更好、更快的康复很重要。术后皮层脑电图(ECoG)和脑电图(EEG)与临床结果之间存在正相关。