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评估酒精使用障碍(AUD)个体的整体健康干预措施和方法:一项范围综述方案

Assessing Holistic Health Interventions and Approaches for Individuals with Alcohol Use Disorder (AUD): Protocol for a Scoping Review.

作者信息

Nanda Shubhi, Roberts Anna, Butera Gisela, Barnett Donna, Wallen Gwenyth R, Barb Jennifer J

出版信息

medRxiv. 2025 Jun 5:2025.06.04.25328277. doi: 10.1101/2025.06.04.25328277.

Abstract

INTRODUCTION

Alcohol Use Disorder (AUD) is a complex condition that requires a multidisciplinary approach to treatment. A comprehensive plan must address the physical, emotional, and mental health of the individual, which is where holistic health comes into play. Holistic health is a system of wellness that considers the whole person-body, mind, and spirit-and aims to restore balance and well-being through the combination of physical, mental, and emotional care. This approach typically incorporates natural and alternative forms of treatment along with conventional medical treatment. In recent years, there has been growing interest in integrating holistic health strategies into addiction treatment. The primary aim of this scoping review is to identify and characterize holistic health interventions currently implemented in the treatment for individuals with AUD. A secondary aim of this review is to collate the efficacy of the interventions as a treatment modality for people with AUD. Additionally, this review will identify gaps in the literature and suggest potential areas for future research.

METHODS AND ANALYSIS

The review will adhere to the Arksey and O'Malley methodological guidelines for scoping reviews. Published research and pilot clinical trials that report on the utilization of holistic health interventions in AUD will be the focus of the search strategy. A total of 5 databases were searched: PubMed/MEDLINE, Embase, CINAHL, Web of Science, and Scopus. After screening, data will be extracted and synthesized from the included studies according to the guidelines developed in this protocol.There will be no date restrictions used in the search. There is a language restriction of only articles published in English. To be included in the study, at least one type of a holistic intervention treatment (e.g., meditation, homeopathy, special diets, etc.) must have been employed. Excluded from the review will be any population that does not have hazardous drinking behaviors as associated with AUD, as well as any pharmaceutical interventions that are not coupled with a holistic intervention. The review itself will be an iterative process completed by two reviewers, and tie breakers will be done through discussions between the two reviewers to come to a unanimous consensus. Documents will be undergoing a risk assessment of bias for the authors to comment on the quality of the literature in this area. Finally, results will be discussed with all coauthors.

ETHICS AND DISSEMINATION

This review will provide an overview of holistic therapies and interventions used to treat AUD, aiming to clarify their roles and effectiveness to support recovery. This review seeks to identify gaps in the literature and will recommend areas for additional research by identifying the strategies currently in use. The results of this review will be published in a peer-reviewed journal and made accessible to a general audience. No ethical approval is needed because this is a scoping review of the material that is already accessible.

ARTICLE SUMMARY

A framework is outlined to extract information for holistic health interventions used for the treatment of alcohol use disorder while assessing the efficacy of the approaches compiled from this review. This review will also collate treatments that are used in concert with pharmacological intervention approaches for the treatment of AUD.This scoping review will be conducted using established methodological frameworks, including the Arksey and O'Malley framework and the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) checklist, to ensure transparency and reproducibility of the process.The aim is to synthesize a wide range of interventions using diverse Medical Subject Headings (MeSH) to better characterize the development of these interventions in a heterogeneous population.A standardized data extraction form will be used to systematically capture and synthesize relevant study characteristics and outcomes across sources, supporting structured summarization by the review team.The reviewers represent a range of perspectives and academic backgrounds, which will help to address any bias in terms of the interpretation of the reviewed studies.Due to resource and reviewer language constraints, only English-language articles will be included, which may limit the generalizability and global applicability of the review findings.

摘要

引言

酒精使用障碍(AUD)是一种复杂的病症,需要多学科方法进行治疗。全面的计划必须关注个体的身体、情感和心理健康,这正是整体健康发挥作用之处。整体健康是一种健康体系,它考虑人的整体——身体、心理和精神——并旨在通过结合身体、心理和情感护理来恢复平衡和健康。这种方法通常将自然和替代治疗形式与传统医学治疗相结合。近年来,将整体健康策略纳入成瘾治疗的兴趣日益浓厚。本范围综述的主要目的是识别和描述目前在AUD个体治疗中实施的整体健康干预措施。本综述的次要目的是整理这些干预措施作为AUD患者治疗方式的疗效。此外,本综述将识别文献中的空白,并提出未来研究的潜在领域。

方法与分析

本综述将遵循Arksey和O'Malley的范围综述方法指南。已发表的研究和报告AUD中整体健康干预措施使用情况的试点临床试验将是搜索策略的重点。共搜索了5个数据库:PubMed/MEDLINE、Embase、CINAHL、Web of Science和Scopus。筛选后,将根据本方案制定的指南从纳入研究中提取和综合数据。搜索将不设日期限制。语言限制仅为英文发表的文章。要纳入研究,必须采用至少一种整体干预治疗(如冥想、顺势疗法、特殊饮食等)。本综述将排除任何不具有与AUD相关的危险饮酒行为的人群,以及任何未与整体干预相结合的药物干预。综述本身将是一个由两名评审员完成的迭代过程,如有分歧将通过两名评审员之间的讨论达成一致共识。将对文献进行作者偏见风险评估,以评论该领域文献的质量。最后,将与所有共同作者讨论结果。

伦理与传播

本综述将概述用于治疗AUD的整体疗法和干预措施,旨在阐明它们在支持康复方面的作用和有效性。本综述旨在识别文献中的空白,并通过识别当前使用的策略推荐进一步研究的领域。本综述的结果将发表在同行评审期刊上,并向普通读者公开。由于这是对已可获取材料的范围综述,无需伦理批准。

文章总结

概述了一个框架,用于提取用于治疗酒精使用障碍的整体健康干预措施的信息,同时评估本次综述所汇总方法的疗效。本综述还将整理与药物干预方法联合用于治疗AUD的治疗方法。本范围综述将使用既定的方法框架进行,包括Arksey和O'Malley框架以及PRISMA-ScR(系统评价和元分析扩展的范围综述首选报告项目)清单,以确保过程的透明度和可重复性。目的是使用不同的医学主题词(MeSH)综合各种干预措施,以更好地描述这些干预措施在异质人群中的发展。将使用标准化的数据提取表系统地收集和综合不同来源的相关研究特征和结果,支持综述团队进行结构化总结。评审员代表一系列观点和学术背景,这将有助于解决在解释所审查研究方面的任何偏见。由于资源和评审员语言限制,仅纳入英文文章,这可能会限制综述结果的普遍性和全球适用性。

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