Gajewski Michal, Gmur Maksym, Goliat Weronika, Haraziński Konrad, Jastrzebska Izabela, Sławińska Barbara, Sysło Oliwia, Rubik Nikola, Błecha Zuzanna, Maryniak Nicole
Medicine, Provincial Hospital in Poznań, Poznań, POL.
Internal Medicine, Międzyleski Specialist Hospital in Warsaw, Warsaw, POL.
Cureus. 2025 Aug 25;17(8):e90954. doi: 10.7759/cureus.90954. eCollection 2025 Aug.
Hemolytic uremic syndrome (HUS) is a rare but life-threatening thrombotic microangiopathy in adults, classically characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. While pediatric HUS is commonly associated with Shiga toxin-producing , adult presentations are often atypical and carry a higher risk of progression to chronic kidney disease or death. We present the case of a 49-year-old woman with acute renal failure and features of HUS, managed with hemodialysis and plasma exchange, emphasizing the diagnostic and therapeutic challenges in adult HUS.
溶血性尿毒症综合征（HUS）是成人中一种罕见但危及生命的血栓性微血管病，典型特征为微血管病性溶血性贫血、血小板减少和急性肾损伤三联征。虽然儿童HUS通常与产志贺毒素相关，但成人病例表现往往不典型，进展为慢性肾脏病或死亡的风险更高。我们报告一例49岁患有急性肾衰竭且有HUS特征的女性病例，该病例采用血液透析和血浆置换治疗，强调成人HUS的诊断和治疗挑战。
