Shah Sandesh, Shrestha Joshana, Piya Smriti
Department of Dermatology Nepal Medical College and Teaching Hospital Kathmandu Nepal.
Clin Case Rep. 2025 Sep 26;13(10):e71010. doi: 10.1002/ccr3.71010. eCollection 2025 Oct.
Pityriasis lichenoides et varioliformis acuta (PLEVA) is a rare inflammatory skin disorder, and mucosal involvement is exceptionally uncommon. We present a 15-year-old male who developed PLEVA with facial and mucosal involvement, preceded by fever. Dermoscopy revealed dotted and linear vessels with micaceous scales. Histopathology showed focal parakeratosis, epidermal exocytosis of neutrophils and lymphocytes, and dense inflammatory infiltrates extending into the subcutaneous tissue. The patient responded well to doxycycline, achieving complete resolution, though varioliform scarring and hyperpigmentation remained. This case underscores the rarity of mucosal involvement in PLEVA and highlights the importance of early recognition and treatment to minimize long-term cutaneous damage.