Yang Yanmei, Jia Yu, Fu Songying, Zhang Lu, Xiang Feng, Hu Wanqin, Cao Xuehua
School of Nursing, Chengdu University of Traditional Chinese Medicine, Sichuan, China.
Department of Gynecology Nursing, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan, China.
Front Psychiatry. 2025 Sep 11;16:1640781. doi: 10.3389/fpsyt.2025.1640781. eCollection 2025.
Reliable estimates of the prevalence of premenstrual syndrome (PMS) serve as the basis for adequate prevention and treatment. However, the prevalence of PMS has rarely been synthesized at the Chinese level. We conducted this systematic review and meta-analyses to provide accurate and comprehensive evidence on the prevalence of PMS in China.
PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Information, Chinese Scientific Journal (VIP), Wan fang and China Biology Medicine databases were systematically searched from inception until March 8, 2025. The prevalence of PMS in China was analyzed using a random effects model.
A total of 77 studies (108,178 participants) were included in the meta-analyses. The pooled prevalence of PMS in China was 48% (95% CI, 44-53%). Subgroup analyses revealed significant differences in the prevalence of PMS according to the screening tool, region, setting, and mean age. Meta-regression analyses indicated that using a prospective tool was significantly associated with lower prevalence.
There was a high degree of heterogeneity among the included studies; The included studies were conducted in urban areas; There was significant publication bias in this meta - analyses; Current meta-analyses contain insufficient information on many risk factors for PMS in China.
The findings demonstrate that most Chinese women have PMS. Given the prevalence of PMS in China, future studies should explore its risk and protective factors, provide regular screening, and implement effective preventive and treatment measures for this demographic.
经前综合征(PMS)患病率的可靠估计是充分预防和治疗的基础。然而,中国层面很少对PMS的患病率进行综合分析。我们开展了这项系统评价和荟萃分析,以提供关于中国PMS患病率准确且全面的证据。
从数据库建立至2025年3月8日,系统检索PubMed、Web of Science、Embase、Cochrane图书馆、中国知网、维普、万方和中国生物医学数据库。采用随机效应模型分析中国PMS的患病率。
荟萃分析共纳入77项研究(108,178名参与者)。中国PMS的合并患病率为48%(95%CI,44-53%)。亚组分析显示,根据筛查工具、地区、研究背景和平均年龄,PMS的患病率存在显著差异。Meta回归分析表明,使用前瞻性工具与较低的患病率显著相关。
纳入研究之间存在高度异质性;纳入研究均在城市地区开展;本荟萃分析存在显著的发表偏倚;目前的荟萃分析包含的关于中国PMS许多危险因素的信息不足。
研究结果表明,大多数中国女性患有PMS。鉴于中国PMS的患病率,未来研究应探索其危险因素和保护因素,提供定期筛查,并针对这一人群实施有效的预防和治疗措施。