Passman Justin N, Stack Emily H, Kleyner Robert S, Servider John, Bellow Emily, Seidman Roberta, Mushlin Harry
Department of Neurological Surgery, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York.
Department of Pathology, Division of Neuropathology, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York.
J Neurosurg Case Lessons. 2025 Sep 29;10(13). doi: 10.3171/CASE25333.
Schwannomas are CNS WHO grade 1 benign peripheral nerve sheath tumors. They can occur anywhere in the body where there are peripheral nerves, but they are most common in the vestibular system. To the authors' knowledge, there has been only one previous report of their presentation in the filum terminale.
The author present the case of a 36-year-old man who presented to the emergency department with acute-on-chronic right low back pain and shooting pain to his right groin with radiation to his knee. He was found to have an L1-2 intradural extramedullary lesion on MRI abutting the conus. His preoperative neurological examination was otherwise unremarkable, and he was promptly taken for L1-2 laminectomy and resection of the lesion. Final pathological diagnosis was intradural extramedullary cellular schwannoma, CNS WHO grade 1, of the filum terminale. Postoperative MRI demonstrated gross-total resection. The patient had new urinary fullness and constipation, which resolved by the 2-month follow-up, and otherwise recovered well with resolution of his back and leg pain.
This case illustrates a rare presentation of an intradural extramedullary cellular schwannoma at the filum terminale, emphasizing the importance of a broad differential diagnosis. Resection of these neoplasms offers a definitive and safe treatment. https://thejns.org/doi/10.3171/CASE25333.
施万细胞瘤是中枢神经系统世界卫生组织1级良性外周神经鞘瘤。它们可发生于身体任何有外周神经的部位,但最常见于前庭系统。据作者所知,此前仅有一篇关于其在终丝部位表现的报道。
作者报告了一例36岁男性患者,该患者因慢性右下腹疼痛急性发作并伴有右腹股沟放射性刺痛至膝关节而就诊于急诊科。MRI检查发现其L1-2节段硬膜内髓外病变紧邻圆锥。其术前神经系统检查无其他异常,随后立即接受了L1-2椎板切除术及病变切除术。最终病理诊断为终丝部位的硬膜内髓外细胞性施万细胞瘤,中枢神经系统世界卫生组织1级。术后MRI显示肿瘤全切。患者出现了新的尿潴留和便秘,在2个月的随访中症状缓解,其他方面恢复良好,腰腿痛症状消失。
该病例说明了终丝部位硬膜内髓外细胞性施万细胞瘤的罕见表现,强调了广泛鉴别诊断的重要性。切除这些肿瘤可提供明确且安全的治疗方法。https://thejns.org/doi/10.3171/CASE25333 。