牛黏液分泌物中免疫球蛋白的起源。
The origins of the immunoglobulins in the mucous secretions of cattle.
作者信息
Curtain C C, Clark B L, Dufty J H
出版信息
Clin Exp Immunol. 1971 Feb;8(2):335-44.
Abstract
The predominating immunoglobulin in the mucous secretions of cattle appears to be IgG1. Radioactive tracer studies using I-labelled IgG1 and I-labelled IgG2 suggest that the larger part of this immunoglobulin is not derived from the plasma but is locally synthesized. Immunofluorescence studies indicate that this immunoglobulin is produced by lymphoid cells which can be observed in the lamina propria and at the base of the villi in the mucosae of the gut and respiratory system. There appears to be some degree of selectivity of transport of IgG1 from the plasma compared with IgG2, although this varies with the tissues.
摘要
牛黏液分泌物中占主导地位的免疫球蛋白似乎是IgG1。使用碘标记的IgG1和碘标记的IgG2进行的放射性示踪研究表明，这种免疫球蛋白的大部分并非来自血浆，而是在局部合成的。免疫荧光研究表明，这种免疫球蛋白是由淋巴样细胞产生的，这些细胞可见于肠道和呼吸系统黏膜固有层及绒毛基部。与IgG2相比，IgG1从血浆中的转运似乎存在一定程度的选择性，不过这因组织而异。
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本文引用的文献
1
Improved sampling method for demonstration of local antibodies in the vagina.
Nature. 1951 Jul 28;168(4265):171-2. doi: 10.1038/168171c0.
2
Preparation of iodine-131 labelled human growth hormone of high specific activity.
Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.
3
A simple chromatographic method for preparation of gamma globulin.
Proc Soc Exp Biol Med. 1960 Jan;103:250-2. doi: 10.3181/00379727-103-25476.
4
Immune electrophoretic analysis of bovine milk and purified bovine milk protein fractions.
Experientia. 1959 Oct 15;15:377-9. doi: 10.1007/BF02158961.
5
THE NORMAL HUMAN INTESTINAL MUCOSA AS A MAJOR SOURCE OF PLASMA CELLS CONTAINING GAMMA-A-IMMUNOGLOBULIN.
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6
7
GAMMA GLOBULINS OF BOVINE LACTEAL SECRETIONS.
Arch Biochem Biophys. 1964 Nov;108:230-9. doi: 10.1016/0003-9861(64)90380-7.
8
ARTIFICIAL STIMULATION OF RESISTANCE TO BOVINE VIBRIOSIS: USE OF BACTERINS.
Am J Vet Res. 1964 Mar;25:371-3.
9
ARTIFICIAL STIMULATION OF RESISTANCE TO BOVINE VIBRIOSIS.
Am J Vet Res. 1963 Sep;24:951-5.
10
A solid phase disc radioimmunoassay for human growth hormone.
J Lab Clin Med. 1967 Nov;70(5):820-30.
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