Curtain C C, Clark B L, Dufty J H
Clin Exp Immunol. 1971 Feb;8(2):335-44.
The predominating immunoglobulin in the mucous secretions of cattle appears to be IgG1. Radioactive tracer studies using I-labelled IgG1 and I-labelled IgG2 suggest that the larger part of this immunoglobulin is not derived from the plasma but is locally synthesized. Immunofluorescence studies indicate that this immunoglobulin is produced by lymphoid cells which can be observed in the lamina propria and at the base of the villi in the mucosae of the gut and respiratory system. There appears to be some degree of selectivity of transport of IgG1 from the plasma compared with IgG2, although this varies with the tissues.
牛黏液分泌物中占主导地位的免疫球蛋白似乎是IgG1。使用碘标记的IgG1和碘标记的IgG2进行的放射性示踪研究表明，这种免疫球蛋白的大部分并非来自血浆，而是在局部合成的。免疫荧光研究表明，这种免疫球蛋白是由淋巴样细胞产生的，这些细胞可见于肠道和呼吸系统黏膜固有层及绒毛基部。与IgG2相比，IgG1从血浆中的转运似乎存在一定程度的选择性，不过这因组织而异。
