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Clinical studies of the interaction between tolmetin and glibenclamide.

作者信息

Chlud K, Kaik B

出版信息

Int J Clin Pharmacol Biopharm. 1977 Sep;15(9):409-10.

PMID:410740
Abstract

Forty patients with diabetes mellitus and rheumatic disorders (rheumatoid arthritis, osteoarthritis, soft-tissue rheumatism) were included in a double-blind trial with the purpose of investigating whether the concomitant administration of tolmetin and glibenclamide leads to an interaction. No significant alterations of blood and urine glucose values could be found in comparison to placebo. Therefore it can be assumed that there is no interaction between these two substances.

摘要

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引用本文的文献

1
Adverse drug interactions with nonsteroidal anti-inflammatory drugs (NSAIDs). Recognition, management and avoidance.非甾体抗炎药(NSAIDs)的药物不良相互作用。识别、管理与避免。
Drug Saf. 1993 Feb;8(2):99-127. doi: 10.2165/00002018-199308020-00002.
2
Clinical pharmacokinetics of non-steroidal anti-inflammatory drugs.非甾体抗炎药的临床药代动力学
Clin Pharmacokinet. 1983 Jul-Aug;8(4):297-331. doi: 10.2165/00003088-198308040-00003.
3
Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs.非甾体抗炎药的药代动力学药物相互作用。
Clin Pharmacokinet. 1990 Jul;19(1):44-66. doi: 10.2165/00003088-199019010-00004.
4
Tolmetin: a review of its pharmacological properties and therapeutic efficacy in rheumatic diseases.托美丁:其药理学特性及在风湿性疾病中的治疗效果综述
Drugs. 1978 Jun;15(6):429-50. doi: 10.2165/00003495-197815060-00002.