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肺结核间歇药物治疗的一般考量

General considerations in intermittent drug therapy of pulmonary tuberculosis.

作者信息

Fox W

出版信息

Postgrad Med J. 1971 Nov;47(553):729-36. doi: 10.1136/pgmj.47.553.729.

DOI:10.1136/pgmj.47.553.729
PMID:4110537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2467339/
Abstract

The advantages of intermittent chemotherapy for pulmonary tuberculosis are discussed and the results of several controlled trials summarized. Once-weekly therapy now appears a definite prospect. The most appropriate approach to therapy at both national and individual physician level now seems to be a combination of unsupervised daily and supervised intermittent regimens.

摘要

讨论了肺结核间歇化疗的优势，并总结了几项对照试验的结果。每周一次的治疗目前看来是一个明确的前景。现在，在国家和个体医生层面，最恰当的治疗方法似乎是将无监督的每日治疗方案和有监督的间歇治疗方案相结合。

相似文献

1
General considerations in intermittent drug therapy of pulmonary tuberculosis.肺结核间歇药物治疗的一般考量
Postgrad Med J. 1971 Nov;47(553):729-36. doi: 10.1136/pgmj.47.553.729.
2
Tuberculosis treatment: dangerous regimens?结核病治疗：危险的治疗方案？
Int J Tuberc Lung Dis. 2001 Jan;5(1):1-3.
3
What about short course and intermittent chemotherapy for tuberculosis in children?儿童结核病的短程和间歇化疗情况如何？
Pediatr Infect Dis. 1982 Sep-Oct;1(5):298-303. doi: 10.1097/00006454-198209000-00003.
4
[Drug therapy of tuberculosis].[结核病的药物治疗]
Dtsch Med Wochenschr. 1974 Aug 9;99(32):1627-30. doi: 10.1055/s-0028-1107999.
5
[Urgent problems of antibacterial treatment of pulmonary tuberculosis].[肺结核抗菌治疗的紧迫问题]
Vrach Delo. 1981 Jan(1):47-9.
6
[Advances and principles in tuberculostatic therapy].
Internist (Berl). 1971 Aug;12(8):328-31.
7
[Chemotherapeutic studies on advanced tuberculosis in mice].[小鼠晚期结核病的化疗研究]
Bibl Tuberc. 1965;21:31-96.
8
[Intermittent chemotherapy of pulmonary tuberculosis (review of the literature)].[肺结核的间歇化疗（文献综述）]
Probl Tuberk. 1978 Oct(10):23-8.
9
Intermittent chemotherapy.间歇性化疗
Tubercle. 1967 Mar;48(1):58-61. doi: 10.1016/s0041-3879(67)80054-0.
10
[Short term chemotherapy of tuberculosis. Evaluation of an 18-week-long treatment including pyrazinamide (preliminary results)].[结核病的短期化疗。对含吡嗪酰胺的18周治疗方案的评估（初步结果）]
Bull Int Union Tuberc. 1978 Dec;53(4):260-1.

引用本文的文献

1
Pharmacokinetic factors in the modern drug treatment of tuberculosis.结核病现代药物治疗中的药代动力学因素
Clin Pharmacokinet. 1999 Aug;37(2):127-46. doi: 10.2165/00003088-199937020-00003.
2
Compliance of patients and physicians: experience and lessons from tuberculosis-II.患者与医生的依从性：结核病防治的经验与教训（二）
Br Med J (Clin Res Ed). 1983 Jul 9;287(6385):101-5. doi: 10.1136/bmj.287.6385.101.
3
Comparative blood levels and metabolism of INH and an INH-matrix preparation in fast and slow inactivators.快速和慢速灭活者中异烟肼及异烟肼基质制剂的血液水平和代谢比较
Can Med Assoc J. 1973 Sep 15;109(6):483-7.

本文引用的文献

1
The Remote Sustained Threshold Therapeutic Action of Streptomycin in Tuberculosis.链霉素在结核病中的远程持续阈值治疗作用。
Science. 1947 Nov 7;106(2758):446-7. doi: 10.1126/science.106.2758.446.
2
FURTHER EXPERIMENTS ON LONG-TERM CHEMOTHERAPY OF ADVANCED MURINE TUBERCULOSIS, WITH EMPHASIS ON INTERMITTENT REGIMES.晚期小鼠结核病长期化疗的进一步实验，重点是间歇疗法。
Tubercle. 1964 Jun;45:125-35. doi: 10.1016/s0041-3879(64)80070-2.
3
Long-term, two-stage chemotherapy of advanced experimental murine tuberculosis with intermittent regimes during the second stage.
Tubercle. 1963 Jun;44:236-40. doi: 10.1016/s0041-3879(63)80118-x.
4
Treatment of experimental murine tuberculosis with different combinations of isoniazid/streptomycin followed by isoniazid alone.用异烟肼/链霉素的不同组合治疗实验性小鼠结核病，随后单独使用异烟肼。
Am Rev Respir Dis. 1962 Aug;86:211-5. doi: 10.1164/arrd.1962.86.2.211.
5
Rate of inactivation of isoniazid in South Indian patients with pulmonary tuberculosis. 3. Serum concentrations of isoniazid produced by three regimens of isoniazid alone and one of isoniazid plus PAS.南印度肺结核患者中异烟肼的失活率。3. 三种单用异烟肼方案及一种异烟肼加对氨基水杨酸方案所产生的异烟肼血清浓度。
Bull World Health Organ. 1961;25(6):793-806.
6
Studies on prevention of experimental tuberculosis with isoniazid. II. Effects of different dosage regimens.异烟肼预防实验性结核病的研究。II. 不同给药方案的效果。
Am Rev Tuberc. 1956 Dec;74(6):917-39. doi: 10.1164/artpd.1956.74.6.917.
7
Acute pulmonary tuberculosis in East Africans: a controlled trial of isoniazid in combination with streptomycin or PAS.东非急性肺结核：异烟肼联合链霉素或对氨基水杨酸的对照试验
Tubercle. 1956 Jun;37(3):151-65. doi: 10.1016/s0041-3879(56)80035-4.
8
The control of experimental mouse tuberculosis by the intermittent administration of streptomycin, viomycin, isoniazid, and streptomycylidene isonicotinyl hydrazine.通过间歇性施用链霉素、紫霉素、异烟肼和链霉素亚甲基异烟酰肼对实验性小鼠结核病进行控制。
Am Rev Tuberc. 1953 Aug;68(2):292-4. doi: 10.1164/art.1953.68.2.292.
9
Control study of comparative efficacy of isoniazid, streptomycin-isoniazid, and streptomycin-para-aminosalicylic acid in pulmonary tuberculosis therapy. III. Report on twenty-eight-week observations on 649 patients with streptomycin-susceptible infections.异烟肼、链霉素-异烟肼和链霉素-对氨基水杨酸治疗肺结核疗效的对照研究。III. 对649例链霉素敏感感染患者28周观察结果的报告
Am Rev Tuberc. 1953 Apr;67(4):539-43. doi: 10.1164/art.1953.67.4.539.
10
[Intermittent treatment of experimental tuberculosis in mice with isonicotinic acid hydrazide].[用异烟肼对小鼠实验性结核病进行间歇治疗]
Ann Inst Pasteur (Paris). 1952 Sep;83(3):397-9.