Otto W, Tautenhahn B, Häntzschel H, Römhild N
Z Gesamte Inn Med. 1977 Jul 15;32(14):343-7.
Due to the unknown etiology of the ankylosing spondylarthritis up to now a causal therapy is not possible. By complex methods of treatment, consisting of chemo- and physiotherapeutic measures we succeed in controlling the course of the disease in as far that the most severe morphological lesions may be prevented. Decisive is the use of a basis therapeutic, in which case chlorochine has been proved favourable. In the last years by optimum dispensary care of these patients with regular controls of the course and controls of the therapy as well as use of all possible rehabilitation measures the premature rate of invalidisation could be reduced from about 50% to 10%. When the disease is recognized in the prodromal phase there exists established hope of preventing severe morphological lesions.
由于迄今为止强直性脊柱炎的病因不明，因此无法进行病因治疗。通过包括化学治疗和物理治疗措施在内的综合治疗方法，我们成功地控制了疾病的进程，从而尽可能预防最严重的形态学损害。关键是使用基础治疗，在这种情况下，氯喹已被证明是有效的。近年来，通过对这些患者进行最佳的门诊治疗，定期监测病情和治疗情况，并采取所有可能的康复措施，过早致残率已从约50%降至10%。当疾病在前驱期被识别时，就有很大希望预防严重的形态学损害。
