Oleĭnik I I, Kraeva E L, Bychkov V A
Zh Mikrobiol Epidemiol Immunobiol. 1977 Oct(10):119-24.
The authors carried out bacteriological studies of the blood, the pleural cavity puncture material, the discharge from the bronchi in bronchoscopy, and also of smears from the nasopharynx of 40 children with acute purulent destruction of the lungs. Staphylococci, often in association with various Gram-negative bacilli, chiefly of the Pseudomonas genus, and Enterobacteriaceae family, prevailed in the cultures of the pathological material. Pathogenic staphylococcus was found in the nasopharynx of patients in 65% of cases. Along with staphylococci in over half of the patients there were revealed Gram-negative bacteria, and yeast-like Candida fungi. In the majority of patients the microbes isolated from the pharynx and the lungs were identical. In these cases bacteriological examination of pharyngeal smears can serve as an auxiliary method of laboratory diagnosis. The isolated straphylococcus strains possessed the majority of the pathogenicity signs; in the great majority of cases they were resistant to the antibiotics the most widely used in the therapeutic practice; among them strains of phage types 80, 54, 75, 77, and 81 prevailed. Thus, at different periods of the disease various types of the microbes prevailed in the materials obtained from the patients. In acute purulent destruction of the lungs bacteriological examination should be carried in dynamics.
作者对40例急性肺化脓性破坏患儿的血液、胸腔穿刺材料、支气管镜检查时支气管分泌物以及鼻咽部涂片进行了细菌学研究。在病理材料培养物中，葡萄球菌常与各种革兰氏阴性杆菌（主要是假单胞菌属和肠杆菌科）一起占优势。65%的患者鼻咽部发现致病性葡萄球菌。超过半数的患者除葡萄球菌外，还发现了革兰氏阴性菌和酵母样念珠菌。大多数患者从咽部和肺部分离出的微生物是相同的。在这些情况下，咽部涂片的细菌学检查可作为实验室诊断的辅助方法。分离出的葡萄球菌菌株具有大多数致病性特征；在绝大多数情况下，它们对治疗实践中最广泛使用的抗生素耐药；其中80、54、75、77和81型噬菌体菌株占优势。因此，在疾病的不同阶段，从患者身上获取的材料中占优势的微生物类型各不相同。在急性肺化脓性破坏时，应动态进行细菌学检查。
