Ramnarain Dharmanand, Deenen Susan, Boerboom Laura, van Oers Jos, Pouwels Sjaak
Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, NLD.
Intensive Care Medicine, Elisabeth Tweesteden Hospital, Tilburg, NLD.
Cureus. 2025 Sep 24;17(9):e93133. doi: 10.7759/cureus.93133. eCollection 2025 Sep.
Acute subarachnoid haemorrhage (SAH) is an acute bleeding in the subarachnoid space in the brain. Due to various pathophysiological sequelae, SAH can be accompanied by acute cardiac failure. Patients who suffer from cardiac failure due to SAH have a high morbidity and mortality. Although the pathophysiology is not completely understood in both clinical and experimental studies, several attempts have been made and published to explain the pathophysiological mechanisms of cardiac failure in SAH patients. Two forms of cardiac failure are described after neurologic injury (like SAH) which are neurogenic stunned myocardium (NSM) with or without diffuse and/or regional wall motion abnormalities (RWMA), and a more specific form called takotsubo cardiomyopathy. This review aims to summarise the current literature on cardiac abnormalities and related pathophysiology in patients with SAH.
急性蛛网膜下腔出血(SAH)是指脑蛛网膜下腔的急性出血。由于各种病理生理后遗症,SAH可伴有急性心力衰竭。因SAH导致心力衰竭的患者发病率和死亡率都很高。尽管临床和实验研究对其病理生理学尚未完全了解,但已经进行了一些尝试并发表文章来解释SAH患者心力衰竭的病理生理机制。神经损伤(如SAH)后会出现两种形式的心力衰竭,即伴有或不伴有弥漫性和/或区域性室壁运动异常(RWMA)的神经源性 stunned 心肌(NSM),以及一种更特殊的形式,称为应激性心肌病。本综述旨在总结目前关于SAH患者心脏异常及相关病理生理学的文献。