白化大鼠对致炎刺激的2-AP（急性期）球蛋白反应中的遗传差异。
Genetic differences in the 2 -AP (acute phase) globulin response to a phlogogenic stimulus in albino rats.
作者信息
Weimer H E, Roberts D M, Comb J C
出版信息
Br J Exp Pathol. 1972 Jun;53(3):253-7.
The responses of the α-AP globulin, albumin, and seromucoid fractions to an inflammatory stimulus have been investigated in the inbred Buffalo, Fisher, and Lewis strains and the random-bred Sprague-Dawley (S), Sprague-Dawley (U) and Wistar strains of albino rats. Strain differences were found with respect to all three fractions. The inbred strains gave stronger responses to the phlogogenic challenge as measured by increased synthesis of the seromucoid fraction, enhanced synthesis of α-AP globulin and the magnitude of the decrease in serum albumin concentrations.
已在近交系布法罗大鼠、费希尔大鼠和刘易斯大鼠以及白化大鼠的随机繁殖斯普拉格-道利（S）品系、斯普拉格-道利（U）品系和Wistar品系中，研究了α-抗胰蛋白酶球蛋白、白蛋白和血清类黏蛋白组分对炎症刺激的反应。发现所有这三个组分均存在品系差异。通过血清类黏蛋白组分合成增加、α-抗胰蛋白酶球蛋白合成增强以及血清白蛋白浓度下降幅度来衡量，近交系大鼠对致炎刺激的反应更强。
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