[注射异种抗肾小管基底膜血清诱导兔肾小管和肾小球肾病]

[Tubular and glomerular nephropathy induced in rabbits by injection of a heterologous antitubular basement membrane serum].

作者信息

Rakotoarivony J, Orfila C, Bardos P, Mahieu P, Muh J P, Suc J M

出版信息

C R Acad Hebd Seances Acad Sci D. 1977 Oct 17;285(9):1017-20.

Abstract

A nephropathy affecting both tubules and glomeruli has been induced in Rabbits by the injection of an heterologous immune serum directed against Rabbit tubular basement membrane. It differs from experimental antiglomerular basement membrane nephropathy by the fixation of antibodies and C3 on tubular basement membrane and by the occurrence of glucosuria.

摘要

通过注射针对兔肾小管基底膜的异种免疫血清，在兔身上诱发了一种同时影响肾小管和肾小球的肾病。它与实验性抗肾小球基底膜肾病的不同之处在于，抗体和补体C3固定在肾小管基底膜上，且出现糖尿。