Paulson G W
Contemp Neurol Ser. 1977;15:169-88.
The thesis of this chapter is that the neurological phenomena discussed and numerous others omitted or not yet recognized relate primarily to a release of primitive activity when diffuse brain damage erodes cerebral inhibition mechanisms. Anatomical correlations are always difficult when there are multiple lesions, and those that have been made have not completely explained these phenomena. A phylogenetic explanation is not completely adequate either but certainly does not bar further investigations. Indeed such a concept points out the necessity to continue to search for other fetal or developmental responses in dementia, to assess the interrelationships between these reflexes, and to quantify the stimulus as well as the response. The prognostic value of these reflexes is not emphasized, because it is not known. In the evaluation of dementia, one of the last obvious frontiers of neurological science, both specific observations and general principles await discovery.
本章的论点是，所讨论的神经学现象以及许多其他被遗漏或尚未被认识到的现象，主要与弥漫性脑损伤侵蚀大脑抑制机制时原始活动的释放有关。当存在多个病变时，解剖学上的关联总是很困难，而且已有的关联并未完全解释这些现象。系统发育学的解释也不完全充分，但肯定不妨碍进一步的研究。事实上，这样一个概念指出了有必要继续在痴呆症中寻找其他胎儿期或发育性反应，评估这些反射之间的相互关系，并对刺激以及反应进行量化。这些反射的预后价值未被强调，因为尚不清楚。在神经科学最后一个明显的前沿领域之一——痴呆症的评估中，具体的观察结果和一般原则都有待发现。
