感染劳斯氏白血病病毒的人类细胞和人类急性白血病细胞上的交叉反应性抗原。
Crossreactive antigens on human cells infected with Rauscher leukemia virus and on human acute leukemia cells.
作者信息
Mann D L, Halterman R, Leventhal B G
出版信息
Proc Natl Acad Sci U S A. 1973 Feb;70(2):495-7. doi: 10.1073/pnas.70.2.495.
Abstract
A water-soluble component of membranes of cells from a Burkitt's lymphoma cultured cell line was used to develop an antiserum that detects an antigen(s) on acute leukemia cells. This antiserum did not react with nonlymphoid cultured cell lines except for human embryonic kidney cells infected with the Rauscher murine leukemia virus. Absorption studies demonstrated this antigen to be crossreactive with the antigen detected on the human acute leukemia cells.
摘要
来自伯基特淋巴瘤培养细胞系的细胞膜水溶性成分被用于制备一种抗血清，该抗血清可检测急性白血病细胞上的一种抗原。除感染劳斯氏鼠白血病病毒的人胚肾细胞外，这种抗血清与非淋巴细胞培养细胞系无反应。吸收研究表明，这种抗原与在人急性白血病细胞上检测到的抗原具有交叉反应性。
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