Krüger H, Malottke R, Potel J
Med Klin. 1977 Oct 28;72(43):1803-7.
In an intensive care unit system comprising three surgical intensive care wards bacteriologic investigations on the presence of Pseudomonas aeruginosa were carried out over a period of 7 months (as an example for the aetiology of hospital infections). Centers of contaminations were found to exist in wet areas and in technical devices (ultrasonic nebulizers, respirators etc.). In many cases, the bacterial strains isolated from patients were found by means of phage-typing to be identical with strains isolated from devices and wet areas. Additional experimental investigations showed the predominant role of ultrasonic nebulizers for germ dissemination. On the basis of the results obtained a patient oriented scheme of probable infection chains was tried to establish. Hereby the wet areas play a central role as reservoirs of germs and therapeutical devices as vectors. The results obtained were evaluated in order to define a catalogue of practical measures for interruption of infection chains.
在一个包含三个外科重症监护病房的重症监护系统中，针对铜绿假单胞菌的存在情况进行了为期7个月的细菌学调查（作为医院感染病因的一个例子）。发现污染源存在于潮湿区域和技术设备（超声雾化器、呼吸机等）中。在许多情况下，通过噬菌体分型发现从患者身上分离出的细菌菌株与从设备和潮湿区域分离出的菌株相同。额外的实验研究表明超声雾化器在病菌传播中起主要作用。根据所获得的结果，尝试建立一个以患者为导向的可能感染链方案。在此，潮湿区域作为病菌储存库发挥核心作用，而治疗设备则作为传播媒介。对所获得的结果进行评估，以便确定一套用于中断感染链的实际措施目录。
