Klein Lauren J, Allen Claire R, Stallings Virginia A
Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, Vanderbilt Institute for Global Health, Nashville, TN, USA.
School of Medicine, Meharry Medical College, Nashville, TN, USA.
Pediatr Clin North Am. 2026 Feb;73(1):173-190. doi: 10.1016/j.pcl.2025.08.016. Epub 2025 Sep 27.
Children with sickle cell disease (SCD) are at increased risk of growth faltering due to elevated energy demands that are often unmet by dietary intake. Effective strategies to address growth faltering emphasize routine growth monitoring, dietary assessment, and screening for food insecurity. Management includes higher-calorie, higher-protein diets, addressing food insecurity, and targeted micronutrient supplementation. Treatments, such as hydroxyurea and transfusions, may further support healthy growth patterns. Referrals to dietitians, pediatric gastroenterologists, and endocrinologists are available to address persistent growth concerns or additional medical issues. Multidisciplinary care and regular monitoring are essential to optimize growth and health outcomes.
患有镰状细胞病（SCD）的儿童因能量需求增加而生长发育迟缓的风险更高，而饮食摄入往往无法满足这些需求。解决生长发育迟缓的有效策略强调定期生长监测、饮食评估以及筛查粮食不安全问题。管理措施包括高热量、高蛋白饮食，解决粮食不安全问题以及有针对性的微量营养素补充。诸如羟基脲和输血等治疗方法可能进一步支持健康的生长模式。可转诊至营养师、儿科胃肠病学家和内分泌学家处，以解决持续存在的生长问题或其他医疗问题。多学科护理和定期监测对于优化生长和健康结果至关重要。
