Ornitz E M
Calif Med. 1973 Apr;118(4):21-47.
This review of the literature on childhood autism discusses the clinical characteristics, differential diagnosis, prognosis and treatment of the autistic behavioral syndrome from a developmental perspective. It includes a discussion of the influence of prenatal and perinatal antecedents, genetic and socio-familial factors, and epidemiologic considerations. Neurologic, electro-encephalographic and experimental neurophysiologic, metabolic, biochemical and hematologic investigations are reviewed. Special emphasis has been given to the changing clinical manifestations which accompany maturation and to the problems of recognition of childhood autism in the very young child.
这篇关于儿童自闭症的文献综述从发育角度探讨了自闭症行为综合征的临床特征、鉴别诊断、预后及治疗。其中包括对产前和围产期因素、遗传及社会家庭因素的影响以及流行病学考量的讨论。还综述了神经学、脑电图及实验神经生理学、代谢、生化和血液学方面的研究。特别强调了随着发育成熟而出现的临床表现变化以及幼儿期自闭症识别方面的问题。