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[罕见乳腺肿瘤]

[Rare breast tumors].

作者信息

Laas E, Darrigues L, Binder J-P, Van-Coppenolle C, Fourchotte V, Feron J-G, Gaillard T, Reyal F, Couturaud B

机构信息

Service de chirurgie sénologique, reconstructrice et gynécologique, Institut Curie, 26, rue d'Ulm, 75005 Paris, France.

Service de chirurgie sénologique, reconstructrice et gynécologique, Institut Curie, 26, rue d'Ulm, 75005 Paris, France.

出版信息

Ann Chir Plast Esthet. 2025 Nov;70(6):581-589. doi: 10.1016/j.anplas.2025.06.002.

DOI:10.1016/j.anplas.2025.06.002
PMID:41232986
Abstract

Rare breast tumors include benign or borderline entities that are often clinically and radiologically misleading. Diagnosis relies in all cases on appropriate biopsy and cross-anatomical-radiological interpretation. Optimal management requires multidisciplinary discussion. Desmoid tumors are non-metastatic but locally aggressive, infiltrative fibroblastic lesions whose management is now based on active surveillance. Idiopathic granulomatous mastitis is a chronic inflammatory mastitis, probably of autoimmune origin, which generally responds to corticosteroid treatment. Phyllodes tumor is a rare fibro-epithelial proliferation, with variable behavior depending on its histological grade, requiring complete excision with negative margins. Radial scarring, a benign sclerosing lesion, can mimic a carcinoma, and sometimes warrants excision depending on the presence of atypia. The aim in managing all these rare tumors is to limit overtreatment, while ensuring personalized follow-up.

摘要

罕见乳腺肿瘤包括良性或交界性病变,这些病变在临床和放射学上常常具有误导性。所有病例的诊断都依赖于恰当的活检以及跨解剖学 - 放射学解释。最佳治疗方案需要多学科讨论。韧带样瘤是非转移性但具有局部侵袭性的浸润性纤维母细胞病变,其治疗目前基于积极监测。特发性肉芽肿性乳腺炎是一种慢性炎症性乳腺炎,可能源于自身免疫,通常对皮质类固醇治疗有反应。叶状肿瘤是一种罕见的纤维上皮增生,其行为因组织学分级而异,需要切缘阴性的完整切除。放射性瘢痕是一种良性硬化性病变,可酷似癌,有时根据异型性的存在情况需要切除。处理所有这些罕见肿瘤的目的是限制过度治疗,同时确保个性化随访。

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