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胆碱能递质物质对体内和体外(14C)-亮氨酸和(3H)-岩藻糖掺入海马总蛋白的影响。

The influence of cholinergic transmitter substances on the incorporation of (14C)-leucine and (3H)-fucose into the total proteins of hippocampus in vivo and in vitro.

作者信息

Jork R, Lössner B, Matthies H

出版信息

Pharmacol Biochem Behav. 1979 Aug;11(2):243-5. doi: 10.1016/0091-3057(79)90022-4.

Abstract

The incorporation of (14C)-leucine into the total proteins of the hippocampus is inhibited by high concentrations of cholinergic agonists, with nicotinic substances (such as 1,1-dimethyl-4-phenyl-piperazine) being more effective than muscarinic compounds (such as arecoline and pilocarpine). Under these conditions the incorporation of (3H)-fucose is not influenced.

摘要

高浓度胆碱能激动剂可抑制(14C)-亮氨酸掺入海马体总蛋白中,其中烟碱类物质(如1,1-二甲基-4-苯基哌嗪)比毒蕈碱类化合物(如槟榔碱和毛果芸香碱)更有效。在这些条件下,(3H)-岩藻糖的掺入不受影响。

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