Lam S K, Tsui J K, Chan P K, Wong K P, Ong G B
Endoscopy. 1977 Nov;9(4):231-4. doi: 10.1055/s-0028-1098523.
In order to determine the risk of bacteraemia from ERCP, we cultured blood specimens from 83 patients before, during and 15 min, 1, 6, 12 and 24 hours after the examination as well as in the subsequent week whenever fever occurred. No bacteraemia was found in the 20 patients who had duodenoscopy only, i.e. in whom ERCP failed. Of the 20 patients with normal biliary and/or pancreatic ducts positive culture was obtained in one patient in whom inadvertent multiple injections of contrast material into the pancreatic duct had resulted in the occurrence of a pyelogram. Four positive cultures were found amongst the 43 patients in whom an obstructive pathology in the biliary or pancreatic system was present. These data support the need of on antibiotic prophylaxis for patients with valvular heart defects.
为了确定内镜逆行胰胆管造影术（ERCP）导致菌血症的风险，我们对83例患者检查前、检查期间、检查后15分钟、1小时、6小时、12小时及24小时的血标本进行培养，并且在检查后的接下来一周内，只要患者出现发热就进行培养。仅接受十二指肠镜检查（即ERCP失败）的20例患者未发现菌血症。在20例胆管和/或胰管正常的患者中，有1例患者因意外多次向胰管内注射造影剂导致肾盂造影而获得阳性培养结果。在43例存在胆管或胰腺系统梗阻性病变的患者中发现4例阳性培养结果。这些数据支持对患有心脏瓣膜缺损的患者进行抗生素预防的必要性。
