Maclean D, Murison J, Griffiths P D
Br Med J. 1973 Dec 29;4(5895):757-61. doi: 10.1136/bmj.4.5895.757.
Serial serum amylase and blood glucose levels were measured in 68 hypothermic (rectal temperature 35 degrees C or less) patients, including 15 who had hypothermic myxoedema (serum protein bound iodine 3.5 mug/100 ml or less). Raised amylase levels were found in 34 patients and probably reflected a mild acute pancreatitis. The high amylase levels correlated with low arterial PO(2) levels and significantly with high arterial PCO(2) levels and the base deficit but not with the severity or duration of the hypothermia. The acute pancreatitis does not explain why hypothermic patients with myxoedema have a poorer prognosis than those who are euthyroid. The pancreatitis occasionally contributed to the development, sometimes delayed, of diabetic ketoacidosis, blood glucose levels of over 120 mg/100 ml being found in 20 patients. There was a significant correlation between the raised serum amylase levels and the hyperglycaemia. Hypoglycaemia, sometimes profound, was found in 12 patients.
对68例体温过低（直肠温度35摄氏度或更低）的患者进行了血清淀粉酶和血糖水平的连续测量，其中包括15例体温过低的黏液性水肿患者（血清蛋白结合碘3.5微克/100毫升或更低）。34例患者的淀粉酶水平升高，这可能反映了轻度急性胰腺炎。高淀粉酶水平与低动脉血氧分压水平相关，与高动脉血二氧化碳分压水平和碱缺失显著相关，但与体温过低的严重程度或持续时间无关。急性胰腺炎并不能解释为什么黏液性水肿的体温过低患者比甲状腺功能正常的患者预后更差。胰腺炎偶尔会导致糖尿病酮症酸中毒的发生，有时会延迟出现，20例患者的血糖水平超过120毫克/100毫升。血清淀粉酶水平升高与高血糖之间存在显著相关性。12例患者出现低血糖，有时低血糖程度较深。
