咖啡因对化学和物理因子诱导的动植物细胞染色体畸变频率的增强作用。 - Suppr

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The enhancement by caffeine of the frequencies of chromosomal aberrations induced in plant and animal cells by chemical and physical agents.

作者信息

Kihlman B A, Sturelid S, Hartley-Asp B, Nilsson K

出版信息

Mutat Res. 1974 Apr;26(2):105-22. doi: 10.1016/s0027-5107(74)80041-2.

DOI:10.1016/s0027-5107(74)80041-2

PMID:4132591

Abstract

摘要

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The enhancement by caffeine of the frequencies of chromosomal aberrations induced in plant and animal cells by chemical and physical agents.咖啡因对化学和物理因子诱导的动植物细胞染色体畸变频率的增强作用。

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The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.咖啡因通过抑制复制后DNA修复，增强了烷化剂诱导的中国仓鼠细胞的细胞死亡、突变和染色体畸变。

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Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.

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Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.

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DNA repair and chromatid anomalies in mammalian cells exposed to 4-nitroquinoline I-oxide.暴露于4-硝基喹啉-1-氧化物的哺乳动物细胞中的DNA修复和染色单体异常

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Effects of caffeine and theophylline on DNA synthesis in unirradiated and UV-irradiated mammalian cells.

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Reduced N-methyl-N'-nitro-N-nitrosoguanidine sister chromatid exchange induction in Chinese hamster V79 cells pre-exposed to 5-bromodeoxyuridine.在预先暴露于5-溴脱氧尿苷的中国仓鼠V79细胞中，N-甲基-N'-硝基-N-亚硝基胍诱导的姐妹染色单体交换减少。

Chromosoma. 1980;76(3):329-38. doi: 10.1007/BF00327270.

Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.小鼠、人类、芥子气与甲基黄嘌呤：咖啡因及相关药物在使人类肿瘤对烷化剂敏感化方面的潜在作用。

Br J Cancer. 1981 May;43(5):669-83. doi: 10.1038/bjc.1981.98.

A schedule to demonstrate radiation-induced sister chromatid exchanges in human lymphocytes.一份展示辐射诱导人淋巴细胞姐妹染色单体交换的时间表。

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Caffeine resistance of Saccharomyces cerevisiae.酿酒酵母的咖啡因抗性

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Mechanism by which caffeine potentiates lethality of nitrogen mustard.咖啡因增强氮芥致死性的机制。

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Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation and increases chromosomal aberrations.镇痛新抑制N-甲基-N'-硝基-N-亚硝基胍诱导的转化并增加染色体畸变。

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6649-53. doi: 10.1073/pnas.77.11.6649.

Effects of a combination of X-rays and caffeine on preimplantation mouse embryos in vitro.X射线与咖啡因联合作用对体外培养的小鼠植入前胚胎的影响。

Radiat Environ Biophys. 1983;22(2):85-93. doi: 10.1007/BF01338888.

Effect of caffeine in G2 on X-ray-induced chromosomal aberrations and mitotic inhibition in ataxia telangiectasia fibroblast and lymphoblastoid cells.咖啡因对共济失调毛细血管扩张症成纤维细胞和淋巴母细胞样细胞中X射线诱导的染色体畸变和有丝分裂抑制的影响。

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Mol Gen Genet. 1984;195(1-2):361-3. doi: 10.1007/BF00332773.

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