马血清诱导肾炎过程中的网状内皮系统清除研究。
Reticuloendothelial clearance studies in the course of horse serum induced nephritis.
作者信息
Wardle E N
出版信息
Br J Exp Pathol. 1974 Apr;55(2):149-52.
Abstract
Assessment of changes in activity of the reticuloendothelial system (RES), including the mesangial cells of the kidney, has been made by means of clearance studies of human aggregated gamma-globulin and of colloidal gold, during the course of horse serum sickness nephritis. RES blockade was found after protein loading and at the phase of circulating immune complexes. At other times RES activity was normal or increased. “Mesangial saturation” may have important implications for human nephritis.
摘要
在马血清病肾炎病程中，通过对人聚合γ-球蛋白和胶体金的清除研究，评估了包括肾系膜细胞在内的网状内皮系统（RES）活性的变化。在蛋白质负荷后和循环免疫复合物阶段发现RES被阻断。在其他时间，RES活性正常或增加。“系膜饱和”可能对人类肾炎具有重要意义。
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