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Studies on the reactivity of the essential cysteine of thymidylate synthetase.

作者信息

Galivan J, Noonan J, Maley F

出版信息

Arch Biochem Biophys. 1977 Dec;184(2):336-45. doi: 10.1016/0003-9861(77)90360-5.

DOI:10.1016/0003-9861(77)90360-5
PMID:413488
Abstract
摘要

相似文献

1
Studies on the reactivity of the essential cysteine of thymidylate synthetase.胸苷酸合成酶必需半胱氨酸的反应活性研究。
Arch Biochem Biophys. 1977 Dec;184(2):336-45. doi: 10.1016/0003-9861(77)90360-5.
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Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacillus casei thymidylate synthetase.
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Kinetics of sulfhydryl group modification of thymidylate synthetase: a proposal for activation of catalytic cysteinly residues.
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Sulfhydryl group modification of thymidylate synthetase and its effect on activity and ternary complex formation.
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Evidence for a sequential interaction of the subunits of thymidylate synthetase.
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Essential tyrosyl residues in Lactobacillus casei thymidylate synthetase.
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Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides.
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Studies on identifying the folylpolyglutamate binding sites of Lactobacillus casei thymidylate synthetase.关于鉴定干酪乳杆菌胸苷酸合成酶的叶酰聚谷氨酸结合位点的研究。
Arch Biochem Biophys. 1982 Jul;216(2):551-8. doi: 10.1016/0003-9861(82)90244-2.
9
Effects of polyoxyanions on sulfhydryl group modification of thymidylate synthetase.
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Fluorine-19 nuclear magnetic resonance investigation of the noncovalent and covalent binary complexes of 5-fluorodeoxyuridylate and Lactobacillus casei thymidylate synthetase.
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引用本文的文献

1
Significance of mutations on the structural perturbation of thymidylate synthase: implications for their involvement in subunit exchange.胸苷酸合成酶结构扰动中突变的意义：对其参与亚基交换的影响。
Protein Sci. 2007 Jul;16(7):1439-48. doi: 10.1110/ps.062509807.
2
Thymidylate synthetase - substrate complex formation.胸苷酸合成酶 - 底物复合物的形成。
Mol Cell Biochem. 1982 Mar 5;43(1):49-57. doi: 10.1007/BF00229539.
3
Thymidylate synthetase purified to homogeneity from human leukemic cells.从人白血病细胞中纯化至同质的胸苷酸合成酶。
Proc Natl Acad Sci U S A. 1979 Feb;76(2):750-4. doi: 10.1073/pnas.76.2.750.