Baker F D, Bush B, Tumasonis C F, Lo F C
Arch Environ Contam Toxicol. 1977;5(2):143-56. doi: 10.1007/BF02220897.
Aroclor 1254 was fed to female and male rats daily for 9 weeks at a dose of 6.4 mg/kg in their drinking water. Control animals received plain tap water plus the emulsified (0.15% Tween 80). Elevated mixed function oxidase (MFO) activity appeared to be due to 2,4,5,2',4',5'- and 2,4,5,2'3'4'-hexachlorobiphenyls, since only these compounds were present to any degree in the tissues of the animals when MFO activity persisted after termination of exposure. The placenta apparently is an effective barrier to PCB transfer.
将Aroclor 1254以6.4毫克/千克的剂量添加到雌雄大鼠的饮用水中，每日喂食9周。对照动物饮用普通自来水并添加乳化剂（0.15%吐温80）。混合功能氧化酶（MFO）活性升高似乎是由2,4,5,2',4',5'-和2,4,5,2'3'4'-六氯联苯引起的，因为在接触终止后MFO活性持续存在时，只有这些化合物在动物组织中达到一定程度的存在。胎盘显然是多氯联苯转移的有效屏障。
