Mérillon J P, Lecarpentier Y, Masquet C, Gourgon R
Arch Mal Coeur Vaiss. 1977 Oct;70(10):1013-20.
This work consists of a comparison of the indices of left ventricular performance measured during the isovolumic nad/or ejection period under changes in load and inotropism, and of the findings on measuring the pressure/volume ratio of the left ventricle. The indices of performance of the left ventricle. The indices of performance of the left ventricle during the ejection phase (ejection fraction, mean speed of fibre shortening, mean standardised speed of systolic ejection) and the ratio pressure/volume were listed for 36 patients, 21 of them before and after perfusion with nitroprussiate, in 6 before and after perfusion of angiotensine, and in 9 from the group before and after post-extra-systolic potentialisation. The indices of left ventricular performance during the isovolumic (formula see text) were measured in 24 of these patients, 15 of them before and after nitroprussiate, and 9 before and after post-extra-systolic potentialisation. These results show that the level of the pressure/volume ratio at the moment of end-systole is independent of the conditions of load--to a greater extent than any other index measured during the isovolumic period or ejectional period--and appears to be thoroughly related to the changes of inotropism.
这项研究包括在负荷和心肌收缩力变化时，对等容期和/或射血期所测得的左心室功能指标进行比较，以及对左心室压力/容积比值测量结果的比较。列出了36例患者在射血期的左心室功能指标（射血分数、平均纤维缩短速度、平均标准化收缩期射血速度）和压力/容积比值，其中21例在硝普钠灌注前后，6例在血管紧张素灌注前后，9例在早搏后电位增强前后。在这些患者中的24例测量了等容期的左心室功能指标（公式见正文），其中15例在硝普钠灌注前后，9例在早搏后电位增强前后。这些结果表明，收缩末期压力/容积比值水平与负荷条件无关——在很大程度上比等容期或射血期所测量的任何其他指标都更无关——并且似乎与心肌收缩力的变化密切相关。
