用小牛胸腺纯化的尿苷 - 胞苷激酶对5 - 氮杂胞苷磷酸化的动力学研究。 - Suppr

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超能文献

Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine-cytidine kinase from calf thymus.

作者信息

Lee T, Karon M, Momparler R L

出版信息

Cancer Res. 1974 Oct;34(10):2482-8.

PMID:4137739

Abstract

摘要

相似文献

Kinetic studies on phosphorylation of 5-azacytidine with the purified uridine-cytidine kinase from calf thymus.用小牛胸腺纯化的尿苷 - 胞苷激酶对5 - 氮杂胞苷磷酸化的动力学研究。

Cancer Res. 1974 Oct;34(10):2482-8.

Metabolism in deoxyribonucleotides. IV. Purification and properties of deoxycytidine kinase of calf thymus.脱氧核糖核苷酸的代谢。IV. 小牛胸腺脱氧胞苷激酶的纯化及性质

J Biochem. 1972 Mar;71(3):485-96.

Uridine-cytidine kinase. IV. Kinetics of the competition between 5-azacytidine and the two natural substrates.

Mol Pharmacol. 1979 Mar;15(2):331-40.

FEEDBACK INHIBITION OF URIDINE KINASE BY CYTIDINE TRIPHOSPHATE AND URIDINE TRIPHOSPHATE.胞苷三磷酸和尿苷三磷酸对尿苷激酶的反馈抑制作用

Biochim Biophys Acta. 1964 Nov 15;91:380-6. doi: 10.1016/0926-6550(64)90067-2.

Enzymatic synthesis of 5-azacytidine 5'-triphosphate from 5-azacytidine.由5-氮杂胞苷酶促合成5-氮杂胞苷5'-三磷酸。

Anal Biochem. 1976 Mar;71(1):60-7. doi: 10.1016/0003-2697(76)90011-7.

Enzymatic phosphorylation of 1-beta-D-arabinofuranosylcytosine.

Cancer Res. 1971 Oct;31(10):1376-82.

Inhibition of uridine-cytidine kinase by 5-azacytidine 5'-triphosphate.5-氮杂胞苷5'-三磷酸对尿苷-胞苷激酶的抑制作用。

Med Pediatr Oncol. 1976;2(3):265-70. doi: 10.1002/mpo.2950020307.

Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.5-氮杂胞苷和5,6-二氢-5-氮杂胞苷的细胞生长抑制作用及代谢的比较研究。

Cancer Res. 1977 Jul;37(7 Pt 1):1956-61.

The metabolism of deoxyribonucleosides in Lactobacillus acidophilus: regulation of deoxyadenosine, deoxycytidine, deoxyguanosine and deoxythymidine kinase activ-ties by nucleotides.嗜酸乳杆菌中脱氧核糖核苷的代谢：核苷酸对脱氧腺苷、脱氧胞苷、脱氧鸟苷和脱氧胸苷激酶活性的调节

Biochim Biophys Acta. 1971 Jan 1;228(1):9-25. doi: 10.1016/0005-2787(71)90542-9.

Properties and cellular distribution of cyclic AMP-dependent protein kinase from thymus.

J Cell Physiol. 1972 Jun;79(3):407-12. doi: 10.1002/jcp.1040790310.

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AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine.AID下调是DNA甲基转移酶抑制剂5-氮杂脱氧胞苷的一种新功能。

Oncotarget. 2014 Jan 15;5(1):211-23. doi: 10.18632/oncotarget.1319.

Expression of nucleoside-metabolizing enzymes in myelodysplastic syndromes and modulation of response to azacitidine.核苷酸代谢酶在骨髓增生异常综合征中的表达及其对阿扎胞苷反应的调节。

Leukemia. 2014 Mar;28(3):621-8. doi: 10.1038/leu.2013.330. Epub 2013 Nov 6.

RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia.RNA 依赖性核糖核苷酸还原酶抑制是 5-氮杂胞苷在急性髓系白血病中活性的主要途径。

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Therapy with azanucleosides for myelodysplastic syndromes.治疗骨髓增生异常综合征的氮杂核苷类药物。

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Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes.一项关于阿扎胞苷和阿糖胞苷联合治疗急性髓系白血病和高危骨髓增生异常综合征的 1/2 期研究报告。

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DNA methylation as a target for drug design.DNA甲基化作为药物设计的靶点。

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