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Studies on the tissue and subcellular distribution of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid, the Lathyrus sativus neurotoxin.

作者信息

Lakshmanan J, Padmanaban G

出版信息

J Neurochem. 1977 Dec;29(6):1121-5. doi: 10.1111/j.1471-4159.1977.tb06517.x.

DOI:10.1111/j.1471-4159.1977.tb06517.x
PMID:413881
Abstract
摘要

相似文献

1
Studies on the tissue and subcellular distribution of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid, the Lathyrus sativus neurotoxin.
J Neurochem. 1977 Dec;29(6):1121-5. doi: 10.1111/j.1471-4159.1977.tb06517.x.
2
Entry of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin into the central nervous system of the adult rat, chick and the rhesus monkey.
J Neurochem. 1978 Jun;30(6):1467-70. doi: 10.1111/j.1471-4159.1978.tb10479.x.
3
Enzymatic formation of 2,3-diaminopropionic acid, the direct precursor of the neurotoxin beta-ODAP, in Lathyrus sativus.在草香豌豆中,神经毒素β-草酰二氨基丙酸的直接前体2,3-二氨基丙酸的酶促形成。
Biol Pharm Bull. 1999 Jul;22(7):770-1. doi: 10.1248/bpb.22.770.
4
Genotypic Variation in the Concentration of β-N-Oxalyl-L-α,β-diaminopropionic Acid (β-ODAP) in Grass Pea (Lathyrus sativus L.) Seeds Is Associated with an Accumulation of Leaf and Pod β-ODAP during Vegetative and Reproductive Stages at Three Levels of Water Stress.在三种水分胁迫水平下,在营养生长和生殖生长阶段,菜豆(Lathyrus sativus L.)种子中β-N-草酰基-L-α,β-二氨基丙酸(β-ODAP)浓度的基因型变异与叶片和豆荚中β-ODAP 的积累有关。
J Agric Food Chem. 2015 Jul 15;63(27):6133-41. doi: 10.1021/acs.jafc.5b01729. Epub 2015 Jun 29.
5
A sensitive and specific colorimetric method for the determination of alpha, beta-diaminopropionic acid and the Lathyrus sativus neurotoxin.一种用于测定α,β-二氨基丙酸和山黧豆神经毒素的灵敏且特异的比色法。
Anal Biochem. 1978 Jun 1;86(2):386-96. doi: 10.1016/0003-2697(78)90762-5.
6
Effect of beta-N-oxalyl-L-alpha, beta-diaminopropionic acid on glutamate uptake by synaptosomes.
Nature. 1974 May 31;249(456):469-71. doi: 10.1038/249469a0.
7
The Lathyrus sativus neurotoxin: evidence of selective retention in monkey tissue.
Toxicol Appl Pharmacol. 1980 Jan;52(1):54-61. doi: 10.1016/0041-008x(80)90247-1.
8
Lathyrus sativus (grass pea) and its neurotoxin ODAP.草豌豆及其神经毒素β-草酰-L-α,β-二氨基丙酸(ODAP)
Phytochemistry. 2006 Jan;67(2):107-21. doi: 10.1016/j.phytochem.2005.10.022. Epub 2005 Dec 5.
9
Determination of neurotoxin 3-N-oxalyl-2,3-diaminopropionic acid and non-protein amino acids in Lathyrus sativus by precolumn derivatization with 1-fluoro-2,4-dinitrobenzene.采用1-氟-2,4-二硝基苯柱前衍生化法测定香豌豆中的神经毒素3-N-草酰基-2,3-二氨基丙酸和非蛋白质氨基酸。
J Chromatogr A. 2000 Jun 23;883(1-2):113-8. doi: 10.1016/s0021-9673(00)00264-8.
10
From soil to brain: zinc deficiency increases the neurotoxicity of Lathyrus sativus and may affect the susceptibility for the motorneurone disease neurolathyrism.从土壤到大脑:锌缺乏会增加香豌豆的神经毒性,并可能影响运动神经元疾病骨软化症的易感性。
Toxicon. 1994 Apr;32(4):461-6. doi: 10.1016/0041-0101(94)90298-4.

引用本文的文献

1
Plant toxin β-ODAP activates integrin β1 and focal adhesion: A critical pathway to cause neurolathyrism.植物毒素 β-ODAP 激活整合素 β1 和黏着斑:导致类破伤风的关键途径。
Sci Rep. 2017 Jan 17;7:40677. doi: 10.1038/srep40677.