儿童神经纤维瘤病的中枢神经表现（作者译）
[Central nervous manifestations of neurofibromatosis in children (author's transl)].
作者信息
Andler W, Roosen K
出版信息
Klin Padiatr. 1977 Nov;189(6):463-6.
PMID:414018
Abstract
Serious central nervous manifestation of neurofibromatosis have been reported in 11 children aged 1,5-12 years. According to the present literature we conclude: 1. Central nervous lesions of neurofibromatosis are common even in childhood. 2. About two thirds of these patients suffer from brain tumors. 3. The tumors involve the suprasellar region in many cases. 4. By this localisation endocrine manifestations, especially precocious puberty, are frequent.
摘要
据报道，11名年龄在1.5至12岁的儿童出现了神经纤维瘤病的严重中枢神经表现。根据现有文献，我们得出以下结论：1. 神经纤维瘤病的中枢神经病变即使在儿童期也很常见。2. 这些患者中约三分之二患有脑肿瘤。3. 肿瘤在许多情况下累及鞍上区域。4. 由于这种定位，内分泌表现，尤其是性早熟很常见。
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