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绵羊瘤胃酸中毒实验中的瘤胃运动

Rumen motility in experimental acidosis of the rumen in sheep.

作者信息

Cebrat E

出版信息

Acta Physiol Pol. 1979 Jul-Aug;30(4):533-41.

PMID:41404
Abstract

In rumen acidosis, induced by infusion of saccharose solution and solutions of different volatile fatty acids and lactic acid into the rumen, and during induced disturbances of acid-base equilibrium in the arterial blood the motility of the dorsal sac of the rumen, the pH of rumen content and the indices of acid-base equilibrium in the arterial blood were investigated. The pH and the indices were determined by the micromethod of Astrup with an Acid-Base-Cart ABC-1 unit. During saccharose-induced acidosis of the rumen the pH of its content was decreased and its motility was strongly inhibited. Acidification of rumen content corresponded to the dissociation constant of a given acid. The motility of the rumen was inhibited most strongly by butyric acid, followed with regard of this effect by acetic acid, propionic acid and lactic acid. It was found that hydrogen ions as well as anions and non-dissociated forms of acids produced in the rumen were responsible for inhibition of this motility and that the rise in the concentration of hydrogen ions in the blood had no inhibitory effect on the motility of the rumen.

摘要

通过向瘤胃内注入蔗糖溶液、不同挥发性脂肪酸溶液和乳酸溶液诱导瘤胃酸中毒,并在诱导动脉血酸碱平衡紊乱期间,对瘤胃背囊的运动性、瘤胃内容物的pH值以及动脉血酸碱平衡指标进行了研究。pH值和各项指标采用Astrup微量法,使用酸碱分析仪ABC - 1型进行测定。在蔗糖诱导的瘤胃酸中毒过程中,瘤胃内容物的pH值降低,其运动性受到强烈抑制。瘤胃内容物的酸化程度与特定酸的解离常数相对应。瘤胃运动性受丁酸抑制最强,其次是乙酸、丙酸和乳酸。研究发现,瘤胃中产生的氢离子以及酸的阴离子和未解离形式是导致这种运动性抑制的原因,而血液中氢离子浓度的升高对瘤胃运动性没有抑制作用。

相似文献

1
Rumen motility in experimental acidosis of the rumen in sheep.绵羊瘤胃酸中毒实验中的瘤胃运动
Acta Physiol Pol. 1979 Jul-Aug;30(4):533-41.
2
Blood acid-base equilibrium in experimental acidosis of the rumen in sheep.绵羊瘤胃酸中毒实验中的血液酸碱平衡
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Am J Vet Res. 1985 Sep;46(9):1908-11.
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