Uroporphyrin formation induced by chlorinated hydrocarbons (lindane, polychlorinated biphenyls, tetrachlorodibenzo-p-dioxin). Requirements for endogenous iron, protein synthesis and drug-metabolizing activity.

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作者信息

Sinclair P R, Granick S

出版信息

Biochem Biophys Res Commun. 1974 Nov 6;61(1):124-33. doi: 10.1016/0006-291x(74)90543-9.

DOI:10.1016/0006-291x(74)90543-9

PMID:4140722

Abstract

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相似文献

Uroporphyrin formation induced by chlorinated hydrocarbons (lindane, polychlorinated biphenyls, tetrachlorodibenzo-p-dioxin). Requirements for endogenous iron, protein synthesis and drug-metabolizing activity.

Biochem Biophys Res Commun. 1974 Nov 6;61(1):124-33. doi: 10.1016/0006-291x(74)90543-9.

Drug-induced porphyrin biosynthesis-XI. Effect of SKF 525-A on the activity of porphyrin-inducing drugs in chick embryos, chickens and rats.药物诱导的卟啉生物合成——XI. 丙磺舒对雏鸡、鸡和大鼠中卟啉诱导药物活性的影响。

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Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria.多氯联苯化合物、2,3,7,8-四氯二苯并对二恶英、苯巴比妥和铁对肝脏尿卟啉原脱羧酶的影响。对卟啉症发病机制的启示。

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Porphyrinogen caeboxy-lyase from chick embryo liver-in vivo effect of heptachlor and lindane.来自鸡胚肝脏的卟啉原羧基裂解酶——七氯和林丹的体内效应

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[Biosynthesis of vitamin B12 and porphyrins by thermophilic methane-forming bacteria].

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Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures.多氯联苯中氯取代位点和构象能对鸡胚肝细胞培养中尿卟啉形成影响的研究。

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Studies of the porphyrin-inducing activity of ethynyl compounds and conformationally restricted and unrestricted analogues of allylisopropylacetamide in chick embryo liver cell culture.乙炔化合物以及烯丙基异丙基乙酰胺的构象受限和不受限类似物在鸡胚肝细胞培养中卟啉诱导活性的研究

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Drug induced porphyrin biosynthesis. IX. Levels of 14C-allylisopropylacetamide, 14C-propylisopropylacetamide and metabolite(s) in the livers of chick embryos and mice.

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Drug-induced porphyrin biosynthesis--XVI. Effects of hydrocortisone, adenosine 3':5'-cyclic monophosphoric acid, its dibutyryl derivative and a phosphodiesterase inhibitor on allylisopropylacetamide-induced porphyrin biosynthesis in chick embryo liver cells maintained in serum-free Waymouth medium.

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引用本文的文献

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Metabolism and biochemical toxicity of PCBs and PBBs.多氯联苯和多溴联苯的代谢与生化毒性。

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Uroporphyrinogen decarboxylase.尿卟啉原脱羧酶

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Porphyrin accumulation in sheep bones associated with 1, 2, 4-trichlorobenzene.

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Synergism of iron and hexachlorobenzene inhibits hepatic uroporphyrinogen decarboxylase in inbred mice.铁与六氯苯的协同作用抑制近交系小鼠肝脏中的尿卟啉原脱羧酶。

Biochem J. 1983 Sep 15;214(3):909-13. doi: 10.1042/bj2140909.

Drug-induced accumulation of uroporphyrin in chicken hepatocyte cultures. Structural requirements for the effect and role of exogenous iron.药物诱导鸡肝细胞培养物中尿卟啉的积累。外源性铁的作用及效应的结构要求。

Biochem J. 1984 Dec 15;224(3):769-77. doi: 10.1042/bj2240769.

Inhibition of uroporphyrinogen decarboxylase by halogenated biphenyls in chick hepatocyte cultures. Essential role for induction of cytochrome P-448.卤代联苯对鸡肝细胞培养物中尿卟啉原脱羧酶的抑制作用。细胞色素P-448诱导的关键作用。

Biochem J. 1984 Sep 15;222(3):737-48. doi: 10.1042/bj2220737.

Biochem J. 1983 Jul 15;214(1):145-51. doi: 10.1042/bj2140145.

Hepatic uroporphyrin accumulation and uroporphyrinogen decarboxylase activity in cultured chick-embryo hepatocytes and in Japanese quail (Coturnix coturnix japonica) and mice treated with polyhalogenated aromatic compounds.培养的鸡胚肝细胞以及用多卤代芳香化合物处理的日本鹌鹑（日本鹌鹑）和小鼠中肝尿卟啉的积累和尿卟啉原脱羧酶活性。

Biochem J. 1988 Jul 1;253(1):131-8. doi: 10.1042/bj2530131.

Increased oxidation of uroporphyrinogen by an inducible liver microsomal system. Possible relevance to drug-induced uroporphyria.可诱导的肝脏微粒体系统使尿卟啉原氧化增加。与药物性卟啉病可能的相关性。

Biochem J. 1988 Feb 15;250(1):161-9. doi: 10.1042/bj2500161.

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