Ebeling H
MMW Munch Med Wochenschr. 1977 Nov 18;119(46):1481-4.
The lack of internationally comparable reference standards for plasma proteins causes problems. For this reason, it is only possible to evaluate the "accuracy" of measurements by comparison of methods. Differences in results which may sometimes be based on technical procedure, physical chemistry or biology are gone into with reference to diagnostically important examples such as albumin, transferrin, ceruloplasmin, fibrinogen and complement 3. It is shown which plasma protein constellations may frequently be expected in certain reactions and what protein patterns have principal importance in clinical practice, e.g. in acute and chronic inflammatory diseases, protein depletion diseases and in liver diseases.
缺乏用于血浆蛋白的国际可比参考标准会引发问题。因此,只能通过方法比较来评估测量的“准确性”。结果差异有时可能基于技术程序、物理化学或生物学因素,本文结合白蛋白、转铁蛋白、铜蓝蛋白、纤维蛋白原和补体3等具有诊断重要性的实例进行探讨。文中指出了在某些反应中可能经常出现的血浆蛋白组合情况,以及在临床实践中(如急性和慢性炎症性疾病、蛋白质消耗性疾病及肝脏疾病)具有主要重要性的蛋白模式。