Krause D, Dittmar K
MMW Munch Med Wochenschr. 1978 Jan 20;120(2-3):69-72.
Earlier investigations have shown that the success of physiotherapeutic exercises in peripheral arterial circulatory disturbances in stage II (Fontaine) can be increased by additional administration of "vasoactive" substances. In the present double-blind study, therefore, 102 outpatients were treated with magnesium nicotinate-magnesium dehydrocholate or a placebo in addition to basic physical therapy. The drug collective (n = 50) showed an increase in walking distance of 24.1% compared with the placebo group (n = 52). Also, in respect to the success rate, the drug collective did better, which, however, may have been due to the unequal distribution of the prognosis factors. Yet it may be concluded that the physiotherapeutic exercises can be effectively supported by the drug tested.
早期研究表明,在II期(Fontaine分期)外周动脉循环障碍中,通过额外给予“血管活性”物质,可以提高物理治疗运动的成功率。因此,在本双盲研究中,102名门诊患者除了接受基础物理治疗外,还接受了烟酸镁-脱氢胆酸镁或安慰剂治疗。与安慰剂组(n = 52)相比,药物组(n = 50)的步行距离增加了24.1%。此外,在成功率方面,药物组表现更好,不过,这可能是由于预后因素分布不均所致。然而,可以得出结论,所测试的药物可以有效地辅助物理治疗运动。